icon fsr

文献詳細

雑誌文献

medicina44巻1号

2007年01月発行

文献概要

今月の主題 高血圧の臨床―焦点の合った個別診療へ向けて 合併症を有する高血圧患者の特徴と有効な降圧療法

睡眠時無呼吸症候群・肥満

著者: 篠邉龍二郎1 若山英雄1 塩見利明1

所属機関: 1愛知医科大学病院睡眠医療センター

ページ範囲:P.144 - P.148

文献購入ページに移動
ポイント

●睡眠時無呼吸症候群患者では睡眠中の血圧は下がりにくく,non-dipper型が多い.

●JNC7では,高血圧の原因としてわかっている疾患のうち,第1番目にSASが列記された.

●血圧コントロール不良例では,SASの合併を疑い,精査すべきである.

●CPAPによって日中の血圧も平均10mmHg程度低下する.

参考文献

1)Kario K, et al:Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives:A prospective study. Circulation 107:1401-1406, 2003
2)Kario K, et al:Stroke prognosis and abnormal nocturnal blood pressure falls in older hypertensives. Hypertension 38:852-857, 2001
3)Sega R, et al:Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population. Circulation 111:1777-1783, 2005
4)Davies CWH, et al:Case-control study of 24 hour ambulatory blood pressure in patients with obstructive sleep apnoea and normal matched control subjects. Thorax 55:736-740, 2000
5)Chobanian AV, et al:The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure:the JNC 7 report. JAMA 289:2560-2572, 2003
6)The International Classification of Sleep Disorders, Second Edition, Diagnostic & Coding Manual, American Academy of Sleep Medicine, Westchester, 2005
7)Marin JM, et al:Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure:An observational study. Lancet 365:1046-1053, 2005
8)He J, et al:Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients. Chest 94:9-14, 1988
9)木村 弘,他:呼吸不全6疾患の全国疫学調査─わが国における肥満低換気症候群の検討─.厚生省特定疾患呼吸不全調査研究班平成9年度研究業績集,pp80-84, 1998
10)Shahar E:Sleep-disordered breathing and cardiovascular disease:cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 163:19-25, 2001
11)Sasanabe R, et al:Metabolic syndrome in Japanese patients with obstructive sleep apnea syndrome. Hypertens Res 29:315-322, 2006
12)Nieto FJ, et al:Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 283:1829-1836, 2000
13)Tanigawa T, et al:Relationship between sleep-disordered breathing and blood pressure levels in community-based samples of Japanese men. Hypertens Res 27:479-484, 2004
14)Vgontzas AN, Bixler EO, Chrousos GP:Sleep apnea is a manifestation of the metabolic syndrome. Sleep Med Rev 9:211-224, 2005
15)Shinohara E, et al:Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects. J Intern Med 241:11-18, 1997
16)Sch●fer H, et al:Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest 122:829-839, 2002
17)Haponik EF, et al:Computerized tomography in obstructive sleep apnea. Correlation of airway size with physiology during sleep and wakefulness. ARRD 127:221-226, 1983
18)Becker HF, et al:Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation 107:68-73, 2003

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1189

印刷版ISSN:0025-7699

雑誌購入ページに移動
icon up
あなたは医療従事者ですか?