medicina44巻8号

2007年08月発行

今月の主題 動脈硬化のトータルマネジメント 臨床に役立つ最近のトピックス

閉塞性動脈硬化症への細胞移植療法

著者： 舘野馨¹ 南野徹¹ 小室一成¹

所属機関： ¹千葉大学大学院医学研究院循環病態医科学

ページ範囲：P.1570 - P.1573

ポイント

●血管再生機序の解明によって近年，虚血性疾患に対する血管再生治療が可能となった．

●血管再生治療には現在，増殖因子補充療法と細胞移植療法とがある．

●いくつかの二重盲検臨床試験により，細胞移植療法の有用性が報告されている．

●合併症に悪性腫瘍や動脈硬化の悪化などが懸念されるため，慎重な経過観察が不可欠である．

●治療機序のより詳細な解明によって治療の有用性・安全性の改善が期待されている．

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