medicina49巻5号

2012年05月発行

今月の主題 糖尿病治療薬2012―皆が知りたい新しい治療A to Z 変化する抗糖尿病薬内服治療

メトグルコで変わるメトホルミン治療

著者： 岡畑純江¹ 柴輝男¹

所属機関： ¹東邦大学医療センター大橋病院糖尿病・代謝内科

ページ範囲：P.791 - P.795

ポイント

★メトグルコの日本人糖尿病治療における役割と展望を概説する．今後のエビデンスの必要性について述べる．

★血糖のみならずメトホルミンにはさまざまな改善効果がある．

★高用量メトホルミンに期待される効果と注意点を記す．

参考文献

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16）加来浩平，他:2型糖尿病患者におけるメトホルミンの使用実態に関する観察研究（MORE study）．糖尿病49:325-331, 2006

17）Garber AJ, et al:Efficacy of metformin in type Ⅱ diabetes；Results of a double-blind, placebo-controlled, dose-response trial. AM J Med 103:491-497, 1997