medicina51巻12号

2014年11月発行

特集 関節リウマチ・膠原病—症例で学ぶ診断と治療

膠原病の診断・治療

多発性筋炎，皮膚筋炎

著者： 綿貫聡¹ 横川直人¹

所属機関： ¹多摩総合医療センターリウマチ膠原病科

ページ範囲：P.2135 - P.2140

文献概要

ポイント

◎筋症状に加えてRaynaud症状，関節症状，間質性肺炎などを呈する抗ARS抗体症候群が存在し，診断には抗ARS抗体の提出が有用である．

◎皮膚筋炎の診断時には，年齢と性別に応じた悪性腫瘍スクリーニングを行う．また再増悪時や治療抵抗性の場合にも，悪性腫瘍の存在や再燃を考慮する．

◎筋症状のない/乏しい皮膚筋炎（CADM）では急速進行性の間質性肺炎の合併に注意する．

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