medicina57巻12号

2020年11月発行

特集 膠原病・自己免疫疾患を「見える化」する 基礎から見える化する

GWASから膠原病を見える化する

著者： 友藤嘉彦¹ 岡田随象¹

所属機関： ¹大阪大学大学院医学系研究科遺伝統計学

ページ範囲：P.2177 - P.2181

Point
◎ゲノムワイド関連解析（GWAS）によって，膠原病・リウマチ性疾患に関連する遺伝子領域が同定されてきた．
◎GWASの結果を生物学的データベースと統合することによって，疾患病態の解明やドラッグ・リポジショニングが可能となる．
◎GWASを個別化医療へ応用する試みがなされている．

参考文献

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