medicina58巻3号

2021年03月発行

特集 いまさら聞けない！ 肝胆膵疾患—みなさんのギモンに答えます 肝硬変の診断と合併症に対する治療

肝硬変の非侵襲的診断—肝硬度の測定

著者： 玉城信治¹ 黒崎雅之¹

所属機関： ¹武蔵野赤十字病院消化器科

ページ範囲：P.442 - P.445

Question 1
肝線維化の程度について，外来診療ではどのような方法で診断すればよいですか？

参考文献

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2）Tamaki N, et al：Clinical utility of Mac-2 binding protein glycosylation isomer in chronic liver diseases. Ann Lab Med 41：16-24, 2021

3）Sandrin L, et al：Transient elastography；A new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol 29：1705-1713, 2003

4）Yada N, et al：Diagnosis of fibrosis and activity by a combined use of strain and shear wave imaging in patients with liver disease. Dig Dis 35：515-520, 2017

5）Hsu C, et al：Magnetic resonance vs transient elastography analysis of patients with nonalcoholic fatty liver disease：A systematic review and pooled analysis of individual participants. Clin Gastroenterol Hepatol 17：630-637.e638, 2019

6）Masuzaki R, et al：Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography. Hepatology 49：1954-1961, 2009

7）Tamaki N, et al：Risk assessment of hepatocellular carcinoma development by magnetic resonance elastography in chronic hepatitis C patients who achieved sustained virological responses by direct-acting antivirals. J Viral Hepat 26：893-899, 2019

8）Tamaki N, et al：Wisteria floribunda agglutinin positive human Mac-2-binding protein as a predictor of hepatocellular carcinoma development in chronic hepatitis C patients. Hepatol Res 45：E82-88, 2015