文献詳細
文献概要
特集 一般医家のための—DOAC時代の心房細動診療 心房細動の病態と診断
心房細動の疫学と病態生理
著者: 三明淳一朗1
所属機関: 1鳥取大学医学部病態解析医学講座 薬理学・薬物療法学分野
ページ範囲:P.2214 - P.2217
文献購入ページに移動Point
◎心房細動の患者数は増加し,2050年には約103万人の患者が予測される.
◎修正可能な危険因子の管理が心房細動発症のリスク低減に役立つ.
◎異常な興奮と不整脈基質の形成が心房細動の病態生理に関与すると理解されている.
◎心房細動の患者数は増加し,2050年には約103万人の患者が予測される.
◎修正可能な危険因子の管理が心房細動発症のリスク低減に役立つ.
◎異常な興奮と不整脈基質の形成が心房細動の病態生理に関与すると理解されている.
参考文献
1)Schnabel RB, et al:50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study;A cohort study. Lancet 386:154-162, 2015
2)Inoue H, et al:Prevalence of atrial fibrillation in the general population of Japan;An analysis based on periodic health examination. Int J Cardiol 137:102-107, 2009
3)Rahman F, et al:Trajectories of risk factors and risk of new-onset atrial fibrillation in the Framingham Heart Study. Hypertension 68:597-605, 2016
4)Latini R, et al:Incidence of atrial fibrillation in a population with impaired glucose tolerance;The contribution of glucose metabolism and other risk factors. A post hoc analysis of the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial. Am Heart J 166:935-940, 2013
5)Fatemi O, et al:Impact of intensive glycemic control on the incidence of atrial fibrillation and associated cardiovascular outcomes in patients with type 2 diabetes mellitus(from the Action to Control Cardiovascular Risk in Diabetes Study). Am J Cardiol 114:1217-1222, 2014
6)Ball J, et al:Sex differences in the impact of body mass index on the risk of future atrial fibrillation;Insights from the longitudinal population-based Tromsø Study. J Am Heart Assoc 7:e008414, 2018
7)Youssef I, et al:Obstructive sleep apnea as a risk factor for atrial fibrillation;A meta-analysis. J Sleep Disord Ther 7:282, 2018
8)Kawasoe S, et al:Uric acid level and prevalence of atrial fibrillation in a Japanese general population of 285, 882. Circ J 80:2453-2459, 2016
9)Suzuki S, et al:Association between smoking habits and the first-time appearance of atrial fibrillation in Japanese patients;Evidence from the Shinken Database. J Cardiol 66:73-79, 2015
10)McManus DD, et al:Alcohol consumption, left atrial diameter, and atrial fibrillation. J Am Heart Assoc 5:e004060, 2016
-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study. Am Heart J 178:45-54, 2016
12)Kokubo Y, et al:Development of a basic risk score for incident atrial fibrillation in a Japanese general population - the Suita Study. Circ J 81:1580-1588, 2017
13)Weng LC, et al:Genetic predisposition, clinical risk factor burden, and lifetime risk of atrial fibrillation. Circulation 137:1027-1038, 2018
14)Lau DH, et al:Modifiable risk factors and atrial fibrillation. Circulation 136:583-596, 2017
15)Anné W, et al:Matrix metalloproteinases and atrial remodeling in patients with mitral valve disease and atrial fibrillation. Cardiovasc Res 67:655-666, 2005
16)Spach MS, Josephson ME:Initiating reentry;The role of nonuniform anisotropy in small circuits. J Cardiovasc Electrophysiol 5:182-209, 1994
17)Healey JS, et al:Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers;A meta-analysis. J Am Coll Cardiol 45:1832-1839, 2005
18)Lim HS, et al:Effect of atrial fibrillation on atrial thrombogenesis in humans;Impact of rate and rhythm. J Am Coll Cardiol 61:852-860, 2013
19)Haïssaguerre M, et al:Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339:659-666, 1998
20)Cox JL, et al:The surgical treatment of atrial fibrillation. Ⅱ. Intraoperative electrophysiologic mapping and description of the electrophysiologic basis of atrial flutter and atrial fibrillation. J Thorac Cardiovasc Surg 101:406-426, 1991
21)Wijffels MC, et al:Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. Circulation 92:1954-1968, 1995
22)Shen MJ, et al:Neural mechanisms of atrial arrhythmias. Nat Rev Cardiol 9:30-39, 2011
掲載誌情報