medicina60巻6号

2023年05月発行

特集 Common diseaseの処方箋ファイル—臨床経過から学ぶ20症例

CASE 10 認知症—物忘れを主訴とする76歳女性

著者： 田丸聡子¹ 原田拓¹

所属機関： ¹練馬光が丘病院総合救急診療科総合診療部門

ページ範囲：P.860 - P.865

76歳女性
主訴　物忘れ．

参考文献

1）日本神経学会：認知症疾患診療ガイドライン2017，医学書院，2017

2）内閣府：令和4年版高齢社会白書．　https://www8.cao.go.jp/kourei/whitepaper/w-2022/zenbun/04pdf_index.html（2023年2月閲覧）

3）内閣府：平成29年版高齢社会白書．　https://www8.cao.go.jp/kourei/whitepaper/w-2017/html/gaiyou/s1_2_3.html（2023年2月閲覧）

4）Schneider LS, et al：Lack of evidence for the efficacy of memantine in mild Alzheimer disease. Arch Neurol 68：991-998, 2011

5）Lockhart IA, et al：Safety and tolerability of donepezil, rivastigmine and galantamine for patients with Alzheimer's disease；Systematic review of the ‘real-world’ evidence. Dement Geriatr Cogn Disord 28：389-403, 2009

6）Bullock R, et al：Rivastigmine and donepezil treatment in moderate to moderately-severe Alzheimer's disease over a 2-year period. Curr Med Res Opin 21：1317, 2005

7）Wilcock G, et al：A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease. Drugs Aging 20：777, 2003

8）Stahl SM, et al：Co-use of donepezil and hypnotics among Alzheimer's disease patients living in the community. J Clin Psychiatry 64：466-472, 2003

9）Regenold WT, et al：Prescribing cholinesterase inhibitors for Alzheimer disease；Timing matters. Am Fam Physician 97：700, 2018

10）Rochon PA, Gurwitz JH：Optimising drug treatment for elderly people；The prescribing cascade. BMJ 315：1096-1099, 1997

11）Parsons C, et al：Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia. Cochrane Database Syst Rev 3：CD009081, 2021

for potentially inappropriate medication use in older adults. J Am Geriatr Soc 67：674-694, 2019

13）Hanlon JT, et al：A method for assessing drug therapy appropriateness. J Clin Epidemiol 45：1045-1051, 1992

14）Reconsidering medication appropriateness for patients late in life. Arch Intern Med 166：605-609, 2006

15）Isik AT, et al：Which cholinesterase inhibitor is the safest for the heart in elderly patients with Alzheimer's disease? Am J Alzheimers Dis Other Demen 27：171-174, 2012

16）Singh S, Dudley C：Discontinuation syndrome following donepezil cessation. Int J Geriatr Psychiatry 18：282-284, 2003