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雑誌文献

medicina60巻6号

2023年05月発行

文献概要

特集 Common diseaseの処方箋ファイル—臨床経過から学ぶ20症例

CASE 14 高尿酸血症—生来健康な41歳男性

著者: 矢吹拓1 青島周一2

所属機関: 1国立病院機構栃木医療センター内科 2中野病院

ページ範囲:P.888 - P.892

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41歳男性
現病歴 生来健康.昨年,職場の人間ドックで尿酸高値を指摘されたものの,気になる自覚症状などはなく医療機関を受診することはなかった.また,5年ほど前に脂肪肝の指摘を受けたこともあったが,それ以外に健康上の問題はなく,医療機関を利用することはほとんどない.

参考文献

1)日本痛風・核酸代謝学会:高尿酸血症・痛風の治療ガイドライン第3版,診断と治療社,2018
2)Joosten LAB, et al:Asymptomatic hyperuricaemia;A silent activator of the innate immune system. Nat Rev Rheumatol 16:75-86, 2020
3)Mackenzie IS, et al:Allopurinol versus usual care in UK patients with ischaemic heart disease(ALL-HEART);A multicentre, prospective, randomised, open-label, blinded-endpoint trial. Lancet 400:1195-1205, 2022
4)Mackenzie IS, et al:Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout(FAST);A multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet 396:1745-1757, 2020
5)Li Q, et al:Diagnosis and treatment for hyperuricemia and gout;A systematic review of clinical practice guidelines and consensus statements. BMJ Open 9:e026677, 2019
6)Brucato A, et al:Management of hyperuricemia in asymptomatic patients;A critical appraisal. Eur J Intern Med 74:8-17, 2020
7)Choi HK, et al:Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 350:1093-1103, 2004
8)Sundy JS, et al:Reduction of plasma urate levels following treatment with multiple doses of pegloticase(polyethylene glycol-conjugated uricase)in patients with treatment-failure gout;Results of a phase Ⅱ randomized study. Arthritis Rheum 58:2882-2891, 2008
9)Borstad GC, et al:Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. J Rheumatol 31:2429-2432, 2004
10)Taylor TH, et al:Initiation of allopurinol at first medical contact for acute attacks of gout;A randomized clinical trial. Am J Med 125:1126-1134, 2012
11)Terkeltaub RA, et al:High versus low dosing of oral colchicine for early acute gout flare;Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum 62:1060-1068, 2010
12)Shekelle PG, et al:Management of gout;A systematic review in support of an American College of Physicians Clinical Practice Guideline. Ann Intern Med 166:37-51, 2017
13)O'Dell JR, et al:Comparative effectiveness of allopurinol and febuxostat in gout management. NEJM Evid 1:10.1056/evidoa2100028, 2022
58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan;National prospective cohort study. BMJ 351:h4848, 2015
15)White WB, et al:Cardiovascular safety of febuxostat or allopurinol in patients with gout. N Engl J Med 378:1200-1210, 2018

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1189

印刷版ISSN:0025-7699

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