medicina61巻5号

2024年04月発行

特集 腎機能を考慮した内科疾患の診療 治療・薬物療法が腎機能の影響を受けやすい内科的疾患 〈消化器疾患〉

消化器系薬剤と腎機能

著者： 住田圭一¹

所属機関： ¹テネシー大学ヘルスサイエンスセンター腎臓内科

ページ範囲：P.732 - P.736

Point
◎プロトンポンプ阻害薬（PPI）の使用は慢性腎臓病（CKD）発症や進展のリスクとなる可能性がある．
◎CKD患者では便秘の合併頻度が高く，高カリウム血症やCKD進展のリスクとなる．
◎CKD患者で酸化マグネシウム製剤を使用する際は，高マグネシウム血症に注意が必要である．
◎下剤による便秘治療により，高カリウム血症やCKD進展リスクが軽減される可能性が示唆されている．

参考文献

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