medicina61巻8号

2024年07月発行

特集 “とりあえずスタチン”から脱却！—動脈硬化性疾患一次予防・最新の考え方 治療

non-HDLコレステロール（non-HDL-C），トリグリセライド（TG），HDL-Cを鑑みた動脈硬化性疾患の予防戦略—脂質異常症治療薬の使い分け

著者： 増田大作¹

所属機関： ¹りんくう総合医療センター循環器内科

ページ範囲：P.1254 - P.1261

Point
◎肥満・耐糖能異常の増加により高トリグリセライド（TG）・低HDLコレステロール（HDL-C）血症が増加し，心血管疾患イベントリスクが増加している．
◎残余リスクとしての高レムナント血症の管理にはnon-HDL-C血症に対する治療介入が重要である．
◎高LDLコレステロール（LDL-C）血症が管理された後，残存するnon-HDL-C血症の管理にフィブラート系薬，選択的PPARαモジュレーター，エイコサペンタエン酸（EPA）を用いる．

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