Neurological Surgery 脳神経外科34巻5号

2006年05月発行

研究

MRIにおけるラクナ病変とmicrobleedsとの関係―連続する180症例での検討

著者： 田実謙一郎¹ 横山俊一¹ 田口裕一郎² 楠元和博¹

所属機関： ¹社団法人）鹿児島共済会南風病院脳神経外科 ²社団法人）鹿児島共済会南風病院内科

ページ範囲：P.483 - P.489

Ⅰ．は じ め に

　MRIのラクナ病変に対しては脳卒中の危険因子という理由から，症候の有無にかかわらず抗血小板薬の投与が行われることが多かった．しかしラクナ梗塞が脳内細小動脈病変（small vessel disease）で高血圧の関与が高いこと^10,23)，さらにラクナ梗塞患者はT2^*-weighted gradient-echo magnetic resonance imaging（T2^*強調画像）での無症候性脳内微小出血（microbleeds）の頻度が高いこと^3,8,9)が明らかになるにつれ，その対応は変化している．Microbleedsは脳出血の危険因子としてその意義が明らかにされつつあり¹⁹⁾，ラクナ病変とmicrobleedsの関係を調査することはラクナ病変への対応において臨床的にも有意義と思われる．今回われわれは，連続する180症例においてMRIのラクナ病変とmicrobleedsとの関係を臨床所見，MRI所見より検討した．

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