Neurological Surgery 脳神経外科34巻8号

2006年08月発行

研究

もやもや病に対する血行再建術後急性期の臨床像と脳循環動態：脳灌流MRIを用いた検討

著者： 藤村幹¹ 麦倉俊司² 清水宏明³ 冨永悌二¹

所属機関： ¹東北大学大学院医学研究科神経外科学分野 ²東北大学大学院医学研究科放射線診断科 ³広南病院脳神経外科

ページ範囲：P.801 - P.809

Ⅰ．は じ め に

　もやもや病は両側内頸動脈終末部，前および中大脳動脈近位部が進行性に狭窄・閉塞し，その付近に異常血管網の発達を認める原因不明の疾患である ¹³⁾．浅側頭動脈・中大脳動脈（STA-MCA）吻合術は本疾患による脳虚血を改善するための有効な治療法として広く用いられているが^4,11)，もやもや病に対するバイパス術後急性期の臨床症状や血行再建による急激な血流増加が脳循環代謝に与える影響についてはいまだ不明な点が多い．

　近年，非侵襲的な脳循環動態評価方法として脳灌流MRIが用いられるようになり，もやもや病においても術前の脳循環動態評価における有用性が報告されている^1,14)．しかしながら，もやもや病血行再建術後の脳循環動態評価におけるその有用性についての報告はごく限られている¹⁵⁾．特に術後急性期の脳灌流MRI所見についての報告は渉猟しえない．今回われわれは成人もやもや病手術例に対して脳灌流MRIと¹²³ I-IMP-SPECTを術後急性期に併用し，それらの所見の変化と臨床症状について検討したので報告する．

参考文献

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