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Neurological Surgery 脳神経外科37巻8号

2009年08月発行

文献概要

研究

初回脳血管造影検査で出血源不明の,非外傷性くも膜下出血症例の検討:特に中脳周囲槽くも膜下出血症例のCT上の血腫の局在について

著者: 仲川和彦1 青柳傑1 前原健寿1 玉置正史1 稲次基希1 河野能久1 武川麻紀1 山本信二2 大野喜久郎1

所属機関: 1東京医科歯科大学脳神経外科 2富士吉田市立病院脳神経外科

ページ範囲:P.771 - P.778

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Ⅰ.はじめに

 初回のdigital subtraction angiography(DSA)で出血源が不明の非外傷性のくも膜下出血(subarachnoid hemorrhage:SAH)は,約5~20%の頻度でみられるとされ,これまでも数多くの報告がある2,6,7,10,13).通常,入院時のcomputed tomography(CT)上の血腫の分布所見から,perimesencephalic nonaneurysmal SAH(PMSAH)と,それ以外のnon-PMSAHに分類され,前者は再出血もなく予後良好とされる.PMSAHはオランダのグループのvan Gijnらによって初めて報告され14),その後同グループのRinkelらによってそのCT所見の血腫の特徴的な分布様式が定義された9)

 しかし,PMSAHのCT所見の定義に関して表現上のあいまいさの問題があり,また,必ずしもその定義を満たさないvariantの報告もある12).これらのことを念頭に置き,今回われわれは,当科で経験した初回DSAで出血源が不明のSAH症例を検討した.

参考文献

1)Alén JF, Lagares A, Lobato RD, Gómez PA, Rivas JJ, Ramos A:Comparison between perimesencephalic nonaneurysmal subarachnoid hemorrhage and subarachnoid hemorrhage caused by posterior circulation aneurysms. J Neurosurg 98:529-535, 2003
2)Andaluz N, Zuccarello M:Yield of further diagnostic work-up of cryptogenic subarachnoid hemorrhage based on bleeding patterns on computed tomographic scans. Neurosurgery 62:1040-1047, 2008
3)Ausman JI:Perimesencephalic nonaneurysmal subarachnoid hemorrhage:what is it? What are we missing? Surg Neurol 57:211, 2002 (Editorial)
4)Goergen SK, Barrie D, Sacharias N, Waugh JR:Perimesencephalic subarachnoid haemorrhage:negative angiography and favourable prognosis. Australas Radiol 37:156-160, 1993
5)Hashimoto H, Iida J, Hironaka Y, Okada M, Sakaki T:Use of computerized tomography angiography in patients with subarachnoid hemorrhage in whom subtraction angiography did not reveal cerebral aneurysms. J Neurosurg 92:278-283, 2000
6)Jung JY, Kim YB, Lee JW, Huh SK, Lee KC:Spontaneous subarachnoid haemorrhage with negative initial angiography:review of 143 cases. J Clin Neurosci 13:1011-1017, 2006
7)Little AS, Garrett M, Germain R, Farhataziz N, Albuquerque FC, McDougall CG, Zabramski JM, Nakaji P, Spetzler RF:Evaluation of patients with spontaneous subarachnoid hemorrhage and negative angiography. Neurosurgery 61:1139-1151, 2007
8)Pinto AN, Ferro JM, Canhão P, Campos J:How often is a perimesencephalic subarachnoid haemorrhage CT pattern caused by ruptured aneurysmas? Acta Neurochir (Wien) 124:79-81, 1993
9)Rinkel GJ, Wijdicks EF, Vermeulen M, Ramos LM, Tanghe HL, Hasan D, Meiners LC, van Gijn J:Nonaneurysmal perimesencephalic subarachnoid hemorrhage:CT and MR patterns that differ from aneurysmal rupture. AJNR Am J Neuroradiol 12:829-834, 1991
10)Ruigrok YM, Rinkel GJ, van Gijn J:CT patterns and long-term outcome in patients with an aneurysmal type of subarachnoid hemorrhage and repeatedly negative angiograms. Cerebrovascular Dis 14:221-227, 2002
11)Schwartz TH, Solomon RA:Perimesencephalic nonaneurysmal subarachnoid hemorrhage:review of the literature. Neurosurgery 39:433-440, 1996
12)Schwartz TH, Mayer SA:Quadrigeminal variant of perimesencephalic nonaneurysmal subarachnoid hemorrhage. Neurosurgery 46:584-588, 2000
13)Topcuoglu MA, Ogilvy CS, Carter BS, Buonanno FS, Koroshetz WJ, Singhal AB:Subarachnoid hemorrhage without evident cause on initial angiography studies:diagnostic yield of subsequent angiography and other neuroimaging tests. J Neurosurg 98:1235-1240, 2003
14)van Gijn J, van Dongen KJ, Vermeulen M, Hijdra A:Perimesencephalic hemorrhage:a nonaneurysmal and benign form of subarachnoid hemorrhage. Neurology 35:493-497, 1985

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1251

印刷版ISSN:0301-2603

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