Neurological Surgery 脳神経外科40巻2号

2012年02月発行

症例

髄上皮腫類似の病理像を呈したテント上primitive neuroectodermal tumorの1例

著者： 伊師雪友¹ 鈴木望¹ 高杉和雄¹ 津田宏重¹ 立野正敏² 田中伸哉³

所属機関： ¹北見赤十字病院脳神経外科 ²旭川医科大学病理学講座（現・釧路赤十字病院病理部） ³北海道大学大学院医学研究科腫瘍病理学講座腫瘍病理学分野

ページ範囲：P.159 - P.165

Ⅰ．はじめに

　Primitive neuroectodermal tumor（PNET）は主に小児に発生する稀な脳腫瘍で，組織学的に未分化な腫瘍細胞の密な増殖を認める．胎生期の上衣下層に存在し，神経細胞，グリア細胞，上衣細胞へと分化するgerminal matrix cellを起源とし，しばしば腫瘍細胞はこれら3種類のうちいずれかへの分化を認める． 一方，髄上皮腫（medulloepithelioma）はPNETの範疇の1つに分類され，組織学的には腫瘍細胞が上皮様に配列し，胎生期の神経管に類似した構造を呈する．今回われわれは，髄上皮腫の病理所見に類似した上皮性の分化を伴う，PNET with epithelial differentiationの症例を経験した．組織学的に稀な症例であり，文献的考察を加え報告する．

参考文献

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