Neurological Surgery 脳神経外科44巻4号

2016年04月発行

連載 脳腫瘍Update

（6）Embryonal tumors（胎児性腫瘍)

著者： 岡秀宏¹²

所属機関： ¹北里大学医学部脳神経外科 ²北里大学メディカルセンター

ページ範囲：P.335 - P.345

Ⅰ．はじめに
　胎児性腫瘍は幼弱な中枢神経系組織を模倣し，未熟な構造からなる腫瘍の総称で，主に小児に発生する悪性腫瘍群である．この腫瘍群は成人発生の腫瘍に比して発生数が少ない上，多種多様な遺伝子変化を示し，その分類や治療法について未だ統一がなされているとはいいがたい状況にある．2007年に改定されたWHOの脳腫瘍分類では，以前と比べ胎児性腫瘍のグループが簡潔にまとめられ，①髄芽腫，②中枢神経系原始神経外胚葉性腫瘍（CNS PNET），③非定型奇形腫様/ラブドイド腫瘍（AT/RT）の3腫瘍に大別された．
　本稿ではこれらの胎児性腫瘍について解説するが，誌面の都合上，画像，病理像を十分掲載できないため，成書を参考にしていただきたい．

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