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Neurological Surgery 脳神経外科46巻2号

2018年02月発行

文献概要

症例

もやもや病術後過灌流症候群に続いてwatershed shiftによる脳梗塞を来した1例

著者: 佐藤公俊1 津田賀俊1 三木貴徳1 小林紀方1 山下太郎1 今高清晴1 吉田享司1 清水史記1

所属機関: 1清仁会シミズ病院脳神経外科

ページ範囲:P.123 - P.129

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Ⅰ.はじめに
 Watershed shift(WS)は,もやもや病に対する浅側頭動脈-中大脳動脈(superficial temporal artery-middle cerebral artery:STA-MCA)バイパス術後の,局所脳循環変化による脳虚血の原因の1つとして提唱された概念である7).WSに伴う脳梗塞は,もやもや病に対するバイパス術全体の1.2〜5.7%に起こる7,16).これまでWSを画像で直接確認した報告はない.今回われわれは,成人もやもや病術後に過灌流症候群(cerebral hyperperfusion syndrome:CHPS)を来し,その後WSが原因と考えられる脳梗塞を来した1例を報告する.

参考文献

1) Fujimura M, Kaneta T, Mugikura S, Shimizu H, Tominaga T:Temporary neurologic deterioration due to cerebral hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in patients with adult-onset moyamoya disease. Surg Neurol 67:273-282, 2007
2) Fujimura M, Shimizu H, Mugikura S, Tominaga T:Delayed intracerebral hemorrhage after superficial temporal artery-middle cerebral artery anastomosis in a patient with moyamoya disease:possible involvement of cerebral hyperperfusion and increased vascular permeability. Surg Neurol 71:223-227, 2009
I]iodoamphetamine single-photon emission computed tomography. Neurosurgery 68:957-965, 2011
4) Fujimura M, Inoue T, Shimizu H, Saito A, Mugikura S, Tominaga T:Efficacy of prophylactic blood pressure lowering according to a standardized postoperative management protocol to prevent symptomatic cerebral hyperperfusion after direct revascularization surgery for moyamoya disease. Cerebrovasc Dis 33:436-445, 2012
5) Fujimura M, Niizuma K, Inoue T, Sato K, Endo H, Shimizu H, Tominaga T:Minocycline prevents focal neurological deterioration due to cerebral hyperperfusion after extracranial-intracranial bypass for moyamoya disease. Neurosurgery 74:163-170, 2014
6) Funaki T, Fushimi Y, Takahashi JC, Takagi Y, Araki Y, Yoshida K, Kikuchi T, Miyamoto S:Visualization of periventricular collaterals in moyamoya disease with flow-sensitive black-blood magnetic resonance angiography:preliminary experience. Neurol Med Chir(Tokyo)55:204-209, 2015
7) Hayashi T, Shirane R, Fujimura M, Tominaga T:Postoperative neurological deterioration in pediatric moyamoya disease:watershed shift and hyperperfusion. J Neurosurg Pediatr 6:73-81, 2010
8) Heros RC, Scott RM, Kistler JP, Ackerman RH, Conner ES:Temporary neurological deterioration after extracranial-intracranial bypass. Neurosurgery 15:178-185, 1984
9) Kaku Y, Iihara K, Nakajima N, Kataoka H, Fukuda K, Masuoka J, Fukushima K, Iida H, Hashimoto N:Cerebral blood flow and metabolism of hyperperfusion after cerebral revascularization in patients with moyamoya disease. J Cereb Blood Flow Metab 32:2066-2075, 2012
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11) Ogasawara K, Inoue T, Kobayashi M, Endo H, Fukuda T, Ogawa A:Pretreatment with the free radical scavenger edaravone prevents cerebral hyperperfusion after carotid endarterectomy. Neurosurgery 55:1060-1067, 2004
12) Ohue S, Kumon Y, Kohno K, Watanabe H, Iwata S, Ohnishi T:Postoperative temporary neurological deficits in adults with moyamoya disease. Surg Neurol 69:281-286, 2008
13) Research Committee on the Pathology and Treatment of Spontaneous Occlusion of the Circle of Willis;Health Labour Sciences Research Grant for Research on Measures for Intractable Diseases:Guidelines for diagnosis and treatment of moyamoya disease(spontaneous occlusion of the circle of Willis). Neurol Med Chir(Tokyo)52:245-266, 2012
14) Sasamori T, Kuroda S, Nakayama N, Iwasaki Y:Incidence and pathogenesis of transient cheiro-oral syndrome after surgical revascularization for moyamoya disease. Neurosurgery 67:1054-1060, 2010
15) Sato K, Yamada M, Kuroda H, Yamamoto D, Asano Y, Inoue Y, Fujii K, Kumabe T:Time-of-flight MR angiography for detection of cerebral hyperperfusion syndrome after superficial temporal artery-middle cerebral artery anastomosis in moyamoya disease. AJNR Am J Neuroradiol 37:1244-1248, 2016
16) Tu XK, Fujimura M, Rashad S, Mugikura S, Sakata H, Niizuma K, Tominaga T:Uneven cerebral hemodynamic change as a cause of neurological deterioration in the acute stage after direct revascularization for moyamoya disease:cerebral hyperperfusion and remote ischemia caused by the ‘watershed shift’. Neurosurg Rev 40:507-512, 2017
17) Uchino H, Kuroda S, Hirata K, Shiga T, Houkin K, Tamaki N:Predictors and clinical features of postoperative hyperperfusion after surgical revascularization for moyamoya disease:a serial single photon emission CT/positron emission tomography study. Stroke 43:2610-2616, 2012

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1251

印刷版ISSN:0301-2603

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