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Neurological Surgery 脳神経外科49巻1号

2021年01月発行

文献概要

特集 脳動脈瘤—Q & Aで学ぶ開頭術,血管内治療のコツと使い分け Ⅳ脳動脈瘤治療の使い分け—現状と未来

脳動脈瘤治療の未来

著者: 金子直樹1 立嶋智1

所属機関: 1ロナルドレーガンUCLAメディカルセンター

ページ範囲:P.164 - P.169

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・現在,脳動脈瘤の薬物治療は確立されていないが,破裂には炎症が強くかかわっていることが示唆され,スタチンやアスピリンに注目が向けられている.
・近年登場した新規デバイス(フローダイバーター,W-EB,PulseRider)により,血管内治療の適応はさらに拡大しつつある.
・ロボット支援技術が血管内治療で応用され始めている.放射線被曝の低減だけでなく,将来的には自動化による安全性向上,遠隔治療などの可能性も秘めている.

参考文献

1)Frösen J, et al:Remodeling of saccular cerebral artery aneurysm wall is associated with rupture:histological analysis of 24 unruptured and 42 ruptured cases. Stroke 35:2287-2293, 2004
2)Kleinloog R, et al:RNA sequencing analysis of intracranial aneurysm walls reveals involvement of lysosomes and immunoglobulins in rupture. Stroke 47:1286-1293, 2016
3)Nakaoka H, et al:Gene expression profiling reveals distinct molecular signatures associated with the rupture of intracranial aneurysm. Stroke 45:2239-2245, 2014
4)Aoki T, et al:Pitavastatin suppresses formation and progression of cerebral aneurysms through inhibition of the nuclear factor κB pathway. Neurosurgery 64:357-365;discussion 365-366, 2009
5)Yoshimura Y, et al:Statin use and risk of cerebral aneurysm rupture:a hospital-based case-control study in Japan. J Stroke Cerebrovasc Dis 23:343-348, 2014
6)Suzuki T, et al:Prevention effect of antiplatelets on aneurysm rupture in a mouse intracranial aneurysm model. Cerebrovasc Dis 45:180-186, 2018
7)Hasan DM, et al:Aspirin as a promising agent for decreasing incidence of cerebral aneurysm rupture. Stroke 42:3156-3162, 2011
8)García-Rodríguez LA, et al:Antithrombotic drugs and risk of hemorrhagic stroke in the general population. Neurology 81:566-574, 2013
9)Hostettler IC, et al:Characteristics of unruptured compared to ruptured intracranial aneurysms:a multicenter case-control study. Neurosurgery 83:43-52, 2018
10)Roa JA, et al:Decreased contrast enhancement on high-resolution vessel wall imaging of unruptured intracranial aneurysms in patients taking aspirin. J Neurosurg 2020 Mar 6:1-7[Epub ahead of print]doi:10.3171/2019.12.JNS193023
11)Hasan DM, et al:Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms:preliminary results. J AmHeart Assoc 2:e000019, 2013
12)Samuel N, Radovanovic I:Genetic basis of intracranial aneurysm formation and rupture:clinical implications in the postgenomic era. Neurosurg Focus 47:E10, 2019
13)Pyysalo MJ, et al:Bacterial DNA findings in ruptured and unruptured intracranial aneurysms. Acta Odontol Scand 74:315-320, 2016
14)Hallikainen J, et al:Periodontitis and gingival bleeding associate with intracranial aneurysms and risk of aneurysmal subarachnoid hemorrhage. Neurosurg Rev 43:669-679, 2020
15)Li H, et al:Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms. Nat Commun 11:3218, 2020
16)Guglielmi G, et al:Persistent primitive trigeminal artery-cavernous sinus fistulas:report of two cases. Neurosurgery 27:805-808;discussion 808-809, 1990
17)Guzzardi G, et al:Flow diverter stents with hydrophilic polymer coating for the treatment of acutely ruptured aneurysms using single antiplatelet therapy:preliminary experience. Interv Neuroradiol 26:525-531, 2020
18)Mendes Pereira V, et al:First-in-human, robotic-assisted neuroendovascular intervention. J Neurointerv Surg 12:338-340, 2020
19)Sajja KC, et al:Endovascular robotic:feasibility and proof of principle for diagnostic cerebral angiography and carotid artery stenting. J Neurointerv Surg 12:345-349, 2020
20)Nogueira RG, et al:Robotic assisted carotid artery stenting for the treatment of symptomatic carotid disease:technical feasibility and preliminary results. J Neurointerv Surg 12:341-344, 2020
21)Mahmud E, et al:Demonstration of the safety and feasibility of robotically assisted percutaneous coronary intervention in complex coronary lesions:results of the CORA-PCI Study(Complex Robotically Assisted Percutaneous Coronary Intervention). JACC Cardiovasc Interv 10:1320-1327, 2017
22)Weisz G, et al:Safety and feasibility of robotic percutaneous coronary intervention:PRECISE(Percutaneous Robotically-Enhanced Coronary Intervention)study. J Am Coll Cardiol 61:1596-1600, 2013
23)Roguin A, et al:Brain and neck tumors among physicians performing interventional procedures. Am J Cardiol 111:1368-1372, 2013

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1251

印刷版ISSN:0301-2603

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