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Neurological Surgery 脳神経外科49巻2号

2021年03月発行

文献概要

特集 脳神経画像Critical Findings—おさえておきたい症状とCT/MRI画像所見 Ⅶおさえておきたい特殊画像検査

数値流体力学(CFD)

著者: 鈴木倫明1

所属機関: 1新潟大学脳研究所脳神経外科学教室

ページ範囲:P.425 - P.431

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・脳動脈瘤壁にかかる基本的な血行力学的パラメーターとして,圧力(pressure)と壁面ずり応力(WSS)がある.
・クリッピング術の際に認めることがある脳動脈瘤壁の菲薄部は,high pressureとlow WSSとの関連が言われている.
・動脈硬化部は,血流停滞時間であるrelative residence time(RRT)との関連が言われている.
・コイル塞栓術後の再発には,pressure関連の血行力学的パラメーターとの関係が言われている.
・画像モダリティの進歩(Silent MRAなど)と数値流体力学(CFD)の組み合わせによって,新たな知見が得られる期待がもたれる.

参考文献

1)Steinman DA, et al:Image-based computational simulation of flow dynamics in a giant intracranial aneurysm. AJNR Am J Neuroradiol 24:559-566, 2003
2)Sugiyama S, et al:Blood flow into basilar tip aneurysms:a predictor for recanalization after coil embolization. Stroke 47:2541-2547, 2016
3)Meng H, et al:High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture:toward a unifying hypothesis. AJNR Am J Neuroradiol 35:1254-1262, 2014
4)Sugiyama S, et al:Relative residence time prolongation in intracranial aneurysms:a possible association with atherosclerosis. Neurosurgery 73:767-776, 2013
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11)Murayama Y, et al:Computational fluid dynamics as a risk assessment tool for aneurysm rupture. Neurosurg Focus 47:E12, 2019
12)Spetzler RF, et al:Ten-year analysis of saccular aneurysms in the Barrow Ruptured Aneurysm Trial. J Neurosurg 132:771-776, 2020
13)Nambu I, et al:High pressure in virtual postcoiling model is a predictor of internal carotid artery aneurysm recurrence after coiling. Neurosurgery 84:607-615, 2019
14)Fujimura S, et al:A new combined parameter predicts re-treatment for coil-embolized aneurysms:a computational fluid dynamics multivariable analysis study. J Neurointerv Surg 10:791-796, 2018
15)Takano N, et al:Non-contrast-enhanced silent scan MR angiography of intracranial anterior circulation aneurysms treated with a low-profile visualized intraluminal support device. AJNR Am J Neuroradiol 38:1610-1616, 2017
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1251

印刷版ISSN:0301-2603

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