Neurological Surgery 脳神経外科50巻2号

2022年03月発行

特集 水頭症—脳脊髄液動態への理解と治療に迫る Ⅰ脳脊髄液の生理と解剖

脳脊髄液の産生・吸収機構と脳室拡大の解剖学的メカニズム

著者： 山田茂樹¹²

所属機関： ¹滋賀医科大学脳神経外科学講座 ²東京大学大学院情報学環・生産技術研究所分散数値シミュレーション開発研究室

ページ範囲：P.264 - P.275

Point
・脳脊髄液（CSF）は主に脳内から排出される間質液から生成され，脈絡叢から産生されるCSFはホメオスタシス維持の重要な役割を担っている．
・CSFはくも膜顆粒を介して静脈洞から吸収されるのではなく，硬膜リンパ管から主に吸収される．
・CSFが増加すると，脈絡裂を中心に臨時のCSF交通路が開いて，側脳室と脳底槽・シルビウス裂が一体となって拡大する．

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