Neurological Surgery 脳神経外科50巻2号

2022年03月発行

特集 水頭症—脳脊髄液動態への理解と治療に迫る Ⅰ脳脊髄液の生理と解剖

脳脊髄液分布における水チャンネルの局在と機能

著者： 林康彦¹

所属機関： ¹金沢医科大学脳神経外科学講座

ページ範囲：P.276 - P.286

Point
・脳脊髄液の産生，吸収による分布には水チャンネルが関与している．
・水チャンネルのアクアポリン4（AQP-4）が吸収に，アクアポリン1（AQP-1）が産生に主に関与している．
・脳内に存在するglymphatic systemは脳脊髄液を吸収，組織中の老廃物を除去するリンパ系機構である．

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