Neurological Surgery 脳神経外科50巻2号

2022年03月発行

特集 水頭症—脳脊髄液動態への理解と治療に迫る Ⅱ特発性正常圧水頭症

特発性正常圧水頭症（iNPH）の疫学と遺伝性水頭症

著者： 伊関千書¹

所属機関： ¹山形大学第三内科・高次脳機能科

ページ範囲：P.309 - P.317

Point
・日本の複数地域からの報告より，高齢人口におけるiNPHの有病率は1.6%で，山形県コホートにおける発症率は1.2/1,000人年であった．
・日本のガイドラインのpossible iNPH with MRI supportでは地域に潜在するiNPHを拾い上げられるものの，病院受診率は依然数%である．
・遺伝性水頭症，iNPHのリスク遺伝子により水頭症の病態解明が期待される．

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