Neurological Surgery 脳神経外科51巻4号

2023年07月発行

特集 下垂体腫瘍診療の新フェーズ—変革期の疫学・診断・治療における必須知識 Ⅱ 下垂体腫瘍の疫学・遺伝・病態

頭蓋咽頭腫の疫学・遺伝・病態

著者： 堀口健太郎¹

所属機関： ¹千葉大学医学部附属病院脳神経外科

ページ範囲：P.607 - P.614

Point
・頭蓋咽頭腫は頭蓋咽頭管から発生する良性上皮性腫瘍（WHO grade 1）であり，病理学的にはエナメル上皮腫型と扁平上皮乳頭型に分けられている．
・頭蓋咽頭腫のエナメル上皮腫型と扁平上皮乳頭型では，おのおの異なる遺伝子異常の関与が報告されている．
・頭蓋咽頭腫は，視機能障害，下垂体機能障害，視床下部障害，認知機能障害など多様な症状を呈する．

参考文献

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