Neurological Surgery 脳神経外科51巻5号

2023年09月発行

特集 臨床脳神経外科医にとってのWHO脳腫瘍分類第5版 Ⅲ 成人良性脳腫瘍

非髄膜上皮系の間葉系腫瘍

著者： 大宅宗一¹ 村上千明²

所属機関： ¹埼玉医科大学総合医療センター脳神経外科 ²埼玉医科大学総合医療センター病理部

ページ範囲：P.837 - P.844

Point
・孤立性線維性腫瘍/血管周皮腫という名称が廃止され，孤立性線維性腫瘍（SFT）となった．
・SFTは核分裂数と壊死によりgrade 1〜3に分類される．
・遺伝子異常によって規定される3つの新たな原発性頭蓋内肉腫の診断名が導入された．

参考文献

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2）Stout AP, Murray MR：Hemangiopericytoma：a vascular tumor featuring Zimmermann's pericytes. Ann Surg 116：26-33, 1942

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fusion in solitary fibrous tumors. Nat Genet 45：131-132, 2013

fusion and can be diagnosed by nuclear expression of STAT6 protein. Acta Neuropathol 125：651-658, 2013

gene fusions in solitary fibrous tumor by integrative sequencing. Nat Genet 45：180-185, 2013

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11）Mena H, et al：Hemangiopericytoma of the central nervous system：a review of 94 cases. Hum Pathol 22：84-91, 1991

12）Chen T, et al：Differentiating intracranial solitary fibrous tumor/hemangiopericytoma from meningioma using diffusion-weighted imaging and susceptibility-weighted imaging. Neuroradiology 62：175-184, 2020

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14）Macagno N, et al：Grading of meningeal solitary fibrous tumors/hemangiopericytomas：analysis of the prognostic value of the Marseille grading system in a cohort of 132 patients. Brain Pathol 29：18-27, 2019

fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathol 137：307-319, 2019

16）Ghose A, et al：CNS hemangiopericytoma：a systematic review of 523 patients. Am J Clin Oncol 40：223-227, 2014