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雑誌文献

検査と技術50巻10号

2022年10月発行

文献概要

病気のはなし

非結核性抗酸菌症

著者: 伊藤優志1 森本耕三1

所属機関: 1結核予防会複十字病院

ページ範囲:P.1126 - P.1133

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●非結核性抗酸菌(NTM)は結核菌とらい菌を除く抗酸菌の総称であり,200種類以上の種・亜種が報告されている.

●肺NTM症は基礎疾患のないやせ型の中高年女性を中心に,罹患者数が急増している.

●肺NTM症の診断には,喀痰培養検査で2回以上の陽性を確認する.

●キャピリア® MAC抗体は特異度が高く,補助的診断法として有用性の高い検査である.

●肺MAC症の標準治療は,マクロライド系薬〔クラリスロマイシン(CAM),アジスロマイシン(AZM)〕,リファンピシン(RFP),エタンブトール(EB)の3剤併用療法である.有空洞例や難治例などにはアミノグリコシド系薬を併用する.

参考文献

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19)Jhun BW, Moon SM, Jeon K, et al : Prognostic factors associated with long-term mortality in 1445 patients with nontuberculous mycobacterial pulmonary disease : a 15-year follow-up study. Eur Respir J 55:1900798,2020
20)Morimoto K, Namkoong H, Hasegawa N, et al : Macrolide-Resistant Mycobacterium avium Complex Lung Disease : Analysis of 102 Consecutive Cases. Ann Am Thorac Soc 13:1904-1911,2016
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1375

印刷版ISSN:0301-2611

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