公衆衛生85巻8号

2021年08月発行

特集 高齢者の低栄養予防・フレイル予防

高齢者におけるフレイルの栄養要因—エビデンスと課題

著者： 児林聡美¹ 佐々木敏²

所属機関： ¹HERS M＆S(ヘルス エムアンドエス) ²東京大学大学院医学系研究科社会予防疫学分野

ページ範囲：P.519 - P.525

【ポイント】
◆一定量以上のたんぱく質の習慣的な摂取がフレイルの発症に予防的に働く可能性を示す研究は多い．しかし，まだ結論は得られていない．
◆いくつかのビタミン類ならびに抗酸化栄養素がフレイルの発症に予防的に働く可能性を示した研究がいくつか存在する．
◆地中海食ならびに健康食指数(HEI)の高い食習慣がフレイルの発症に予防的に働く可能性を示す研究がいくつか存在し，今後の結果が期待される．

参考文献

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9)Kobayashi S, et al:Diet with a combination of high protein and high total antioxidant capacity is strongly associated with low prevalence of frailty among old Japanese women:a multicenter cross-sectional study. Nutr J 16:29, 2017

10)Kojima G, et al:Adherence to Mediterranean Diet Reduces Incident Frailty Risk:Systematic Review and Meta-Analysis. J Am Geriatr Soc 66:783-788, 2018

11)Hengeveld LM, et al:Prospective Associations of Diet Quality With Incident Frailty in Older Adults:The Health, Aging, and Body Composition Study. J Am Geriatr Soc 67:1835-1842, 2019

12)佐々木敏：地中海食は和食より健康的か？　地中海食と和食，究極の健康食を探る．佐々木敏の栄養データはこう読む！，第2版．pp241-248，女子栄養大学出版部，2020

13)Murakami K, et al:Reproducibility and Relative Validity of the Healthy Eating Index-2015 and Nutrient-Rich Food Index 9.3 Estimated by Comprehensive and Brief Diet History Questionnaires in Japanese Adults. Nutrients 11:E2540, 2019