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雑誌文献

臨床眼科60巻3号

2006年03月発行

文献概要

連載 今月の話題

加齢黄斑変性に対する光線力学療法の最近の動向

著者: 石川浩平1 寺崎浩子1

所属機関: 1名古屋大学医学部眼科学教室

ページ範囲:P.239 - P.245

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これまで治療に苦慮されてきた滲出型加齢黄斑変性に対する治療法として光線力学療法が本邦でも認可され約1年半が経過し,日本人に対する本治療の効果が明らかになってきた。本稿では,過去の治験の成績,筆者らの施設での治療経過,治療後にみられる網膜の変化,今後の展望について述べる。

参考文献

1)Treatment of Age-Related Macular Degeneration With Photodynamic Therapy(TAP)Study Group:Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin:one-year results of 2 randomized clinical trials-TAP Report 1. Arch Ophthalmol 117:1329-1345, 1999
2)Treatment of Age-Related Macular Degeneration With Photodynamic Therapy(TAP)Study Group:Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin:two-year results of 2 randomized clinical trials-TAP Report 2. Arch Ophthalmol 119:198-207, 2001
3)Treatment of Age-Related Macular Degeneration With Photodynamic Therapy(TAP)Study Group:Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration:additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3. Arch Ophthalmol 120:1443-1454, 2002
4)Treatment of Age-Related Macular Degeneration With Photodynamic Therapy(TAP)Study Group:Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration:three-year results of an open-label extension of 2 randomized clinical trials-TAP Report No. 5. Arch Ophthalmol 120:1307-1314, 2002
5)Verteporfin Roundtable Participants:Guidelines for using verteporfin(Visudyne)in photodynamic therapy for choroidal neovascularization due to age-related macular degeneration and other causes:update. Retina 25:119-134, 2005
6)Verteporfin In Photodynamic Therapy Study Group:Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration:two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy report 2. Am J Ophthalmol 84:244-250, 2000
7)The Japanese Age-Related Macular Degeneration Trial(Jat)Study Group:Japanese age-related macular degeneration trial:1-year results of photodynamic therapy with verteporfin in Japanese patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. Am J Ophthalmol 136:1049-1061, 2003
8)Lee SC, Seong YS, Kim SS et al:Photodynamic therapy with verteporfin for polypoidal choroidal vasculopathy of the macula. Ophthalmologica 218:193-201, 2004
9)Chan WM, Lam DS, Lai TY et al:Photodynamic therapy with verteporfin for symptomatic polypoidal choroidal vasculopathy:one-year results of a prospective case series. Ophthalmology 111:1576-1584, 2004
10)Palmowski AM, Allgayer R, Heinemann-Vernaleken B et al:Influence of photodynamic therapy in choroidal neovascularization of focal retinal function assessed with the multifocal electroretinogram and perimetry. Ophthalmology 109:1788-1792, 2002
11)Ruther K, Breidenbach K, Schwartz R et al:Testing central retinal function with multifocal electroretinography before and after photodynamic therapy. Ophthalmologe 100:459-464, 2003
12)Moschos MN, Panayotidis D, Moschos MM et al:A preliminary assessment of macular function by MF-ERG in myopic eyes with CNV with complete response to photodynamic therapy. Eur J Ophthalmol 13:461-467, 2003
13)Jiang L, Jin C, Wen F et al:The changes of multifocal electroretinography in the early stage of photodynamic therapy for choroidal neovascularization. Doc Ophthalmol 107:165-170, 2003
14)Lai TY, Chan WM, Lam DS:Transient reduction in retinal function revealed by multifocal electroretinogram after photodynamic therapy. Am J Ophthalmol 137:826-833, 2004
15)Schmidt-Erfurth U, Schlotzer-Schrehard U, Cursiefen C et al:Influence of photodynamic therapy on expression of vascular endothelial growth factor(VEGF), VEGF receptor 3, and pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 44:4473-4480, 2003
16)Spaide RF, Sorenson J, Maranan L:Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neo-vascularization. Ophthalmology 110:1517-1525, 2003
17)Rechtman E, Danis RP, Pratt LM et al:Intravitreal triamcinolone with photodynamic therapy for subfoveal choroidal neovascularisation in age related macular degeneration. Br J Ophthalmol 88:344-347, 2004
18)Eyetech Study Group:Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration:phaseⅡ study results. Ophthalmology 110:979-986, 2003

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1308

印刷版ISSN:0370-5579

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