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文献概要
眼底自発蛍光検査は非侵襲的に網膜色素上皮におけるリポフスチンの分布を描出することができる。リポフスチンは視細胞外節の生理的な貪食に伴う代謝産物であり,眼底自発蛍光は網膜色素上皮の代謝機能を反映しているといえる。本稿では眼底自発蛍光検査における各疾患の特徴的な所見や視機能との関連について概説したい。
参考文献
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2)Spaide RF, Klancnik JM:Fundus autofluorescence and central serous chorioretinopathy. Ophthalmology 112:825-833, 2005
3)Popovic P, Jarc-Vidmar M, Hawlina M:Abnormal fundus autofluorescence in relation to retinal function in patients with retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol 243:1018-1027, 2005
4)Robson AG, El-Amir A, Bailey C et al:Pattern ERG correlates of abnormal fundus autofluorescence abnormalities in patients with retinitis pigmentosa and normal visual acuity. Invest Ophthalmol Vis Sci 44:3544-3550, 2003
5)Robson AG, Egan CA, Luong VA et al:Comparison of fundus autofluorescence with photopic and scotopic fine matrix mapping in patients with retinitis pigmentosa and normal visual acuity. Invest Ophthalmol Vis Sci 45:4119-4125, 2004
6)Robson AG, Saihan Z, Jenkins SA et al:Functional characterization and serial imaging of abnormal fundus autofluorescence in patients with retinitis pigmentosa and normal visual acuity. Br J Ophthalmol90:472-479, 2006
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