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臨床眼科64巻1号

2010年01月発行

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iPS細胞と網膜再生

著者: 平見恭彦1 高橋政代1

所属機関: 1理化学研究所発生・再生科学総合研究センター網膜再生医療研究チーム

ページ範囲:P.7 - P.13

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 人工多能性幹細胞(iPS細胞)の最初の報告が世に出てから3年が経過した。発表以来,iPS細胞の利用による再生医療の実現に対する期待が高まっている。ここで,この間のiPS細胞研究,網膜再生研究の進展について解説する。

参考文献

1)Takahashi K, Yamanaka S:Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676, 2006
2)Takahashi K, Tanabe K, Ohnuki M et al:Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872, 2007
3)Okita K, Ichisaka T, Yamanaka S:Generation of germline-competent induced pluripotent stem cells. Nature 448:313-317, 2007
4)Nakagawa M, Koyanagi M, Tanabe K et al:Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26:101-106, 2007
5)Miura K, Okada Y, Aoi T et al:Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 27:743-745, 2009
6)Okita K, Nakagawa M, Hyenjong H et al:Generation of mouse induced pluripotent stem cells without viral vectors. Science 322:949-953, 2008
7)Zhou H, Wu S, Joo JY et al:Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4:381-384, 2009
8)Kim D, Kim CH, Moon JI et al:Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4:472-476, 2009
9)Aasen T, Raya A, Barrero MJ et al:Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 26:1276-1284, 2008
10)Loh YH, Agarwal S, Park IH et al:Generation of induced pluripotent stem cells from human blood. Blood 113:5476-5479, 2009
11)Yamanaka S:Elite and stochastic models for induced pluripotent stem cell generation. Nature 460:49-52, 2009
12)Ikeda H, Osakada F, Watanabe K et al:Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci USA 102:11331-11336, 2005
13)Osakada F, Ikeda H, Mandai M et al:Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells. Nat Biotechnol 26:215-224, 2008
14)Hirami Y, Osakada F, Takahashi K et al:Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 458:126-131, 2009
15)Lund RD, Wang S, Klimanskaya I et al:Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells 8:189-199, 2006
16)Lamba DA, Karl MO, Ware CB et al:Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 103:12769-12774, 2006
17)van Meurs JC, ter Averst E, Hofland LJ et al:Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes. Br J Ophthalmol 88:110-113, 2004
18)Joussen AM, Heussen FM, Joeres S et al:Autologous translocation of the choroid and retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol 142:17-30, 2006
19)MacLaren RE, Uppal GS, Balaggan KS et al:Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration. Ophthalmology 114:561-570, 2007
20)MacLaren RE, Pearson RA, MacNeil A et al:Retinal repair by transplantation of photoreceptor precursors. Nature 444:203-207, 2006
21)Lamba DA, Gust J, Reh TA:Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in crx-deficient mice. Cell Stem Cell 4:73-79, 2009

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1308

印刷版ISSN:0370-5579

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