臨床眼科64巻7号

2010年07月発行

連載 今月の話題

強度近視の病態解明と治療法の進歩

著者： 大野京子¹

所属機関： ¹東京医科歯科大学大学院医歯学総合研究科眼科学

ページ範囲：P.1047 - P.1056

　わが国は世界有数の近視国であり，強度近視は緑内障に次いで第2位の失明原因である。以前は有効な治療法がなかった近視性眼底病変に対しても，近年，抗血管新生療法などの新しい治療法が可能となり，また，光干渉断層計を用いた画像診断技術の進歩に伴い，近視性牽引黄斑症などの新たな病態が解明され，本症に対する硝子体手術がさかんに行われるようになった。同時に，全ゲノムスクリーニングという新しい遺伝子解析技術の進歩により，強度近視の原因遺伝子の全貌が解明されようとしている。強度近視診療は新たな時代に入っており，近い将来，近視性眼底病変の管理は「治療から予防へ」と向かうであろうと期待される。

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