臨床眼科72巻11号

2018年10月発行

増刊号 7年前の常識は現在の非常識！—眼科診療の最新標準 3．緑内障 2）診断

緑内障性視神経症の画像診断

著者： 東出朋巳¹

所属機関： ¹金沢大学附属病院眼科

ページ範囲：P.144 - P.150

ここが変わった！

以前の常識

　●緑内障性視神経症の画像診断のターゲットは，視神経乳頭形状と乳頭周囲網膜神経線維層厚であった。

現在の常識

　●緑内障性視神経症（GON）の画像診断の主要ターゲットは乳頭周囲網膜神経線維層厚と黄斑部網膜内層厚であり，視神経乳頭深部構造，視神経乳頭部血流などが新たに加わった。

参考文献

1）Tan O, Chopra V, Tzu-HuiLu A et al：Detection of macular ganglion cell loss in glaucoma by Fourier domain optical coherence tomography. Ophthalmology 116：2305-2314, 2009

2）Nakatani Y, Higashide T, Ohkubo S et al：Influences of the inner retinal sublayers and analytical areas in macular scans by spectral-domain OCT on the diagnostic ability of early glaucoma. Invest Ophthalmol Vis Sci 55：7479-7485, 2014

3）Traynis I, De Moraes CG, Raza AS et al：Prevalence and nature of early glaucomatous defects in the central 10° of the visual field. JAMA Ophthalmol 32：291-297, 2014

4）Ohkubo S, Higashide T, Udagawa S et al：Focal relationship between structure and function within the central 10 degrees in glaucoma. Invest Ophthalmol Vis Sci 55：5269-5277, 2014

5）Higashide T, Ohkubo S, Hangai M et al：Influence of clinical factors and magnification correction on normal thickness profiles of macular retinal layers using optical coherence tomography. PLoS ONE 11：e0147782, 2016

6）Seol BR, Kim DM, Park KH et al：Assessment of optical coherence tomography color probability codes in myopic glaucoma eyes after applying a myopic normative database. Am J Ophthalmol 183：147-155, 2017

7）Kim YK, Ha A, Na KI et al：Temporal relation between macular ganglion cell-inner plexiform layer loss and peripapillary retinal nerve fiber layer loss in glaucoma. Ophthalmology 124：1056-1064, 2017

8）Bowd C, Zangwill LM, Weinreb RN et al：Estimating optical coherence tomography structural measurement floors to improve detection of progression in advanced glaucoma. Am J Ophthalmol 175：37-44, 2017

9）Lee EJ, Kim TW, Kim M, et al：Recent structural alteration of the peripheral lamina cribrosa near the location of disc hemorrhage in glaucoma. Invest Ophthalmol Vis Sci 55：2805-2815, 2014

10）Park HL, Lee J, Jung Y et al：Optic disc hemorrhage and lamina cribrosa defects in glaucoma progression. Sci Rep 7：3489, 2017

11）Chauhan BC, Danthurebandara VM, Sharpe GP et al：Bruch's membrane opening minimum rim width and retinal nerve fiber layer thickness in a normal white population：A multicenter study. Ophthalmology 122：1786-1794, 2015

12）Kim YW, Lee EJ, Kim TW, et al. Microstructure of β-zone parapapillary atrophy and rate of retinal nerve fiber layer thinning in primary open-angle glaucoma. Ophthalmology 121：1341-1349, 2014

13）Shiga Y, Aizawa N, Tsuda S et al：Preperimetric Glaucoma Prospective Study（PPGPS）：predicting visual field progression with basal optic nerve head blood flow in normotensive PPG eyes. Transl Vis Sci Technol 7：11, 2018

14）Sakaguchi K, Higashide T, Udagawa S et al：Comparison of sectoral structure-function relationships in glaucoma：vessel density versus thickness in the peripapillary retinal nerve fiber layer. Invest Ophthalmol Vis Sci 58：5251-5262, 2017

15）Park HL, Kim JW, Park CK：Choroidal microvasculature dropout is associated with progressive retinal nerve fiber layer thinning in glaucoma with disc hemorrhage. Ophthalmology 125：1003-1013, 2018