臨床眼科72巻13号

2018年12月発行

特集 OCTアンギオグラフィを始めるために—コツと落とし穴

将来への可能性

著者： 寺崎寛人¹ 椎原秀樹¹ 園田祥三¹

所属機関： ¹鹿児島大学医学部眼科学教室

ページ範囲：P.1685 - P.1691

文献概要

はじめに

　未来のことを秩序立てて文章化するのは容易ではないが，われわれ眼科医がその凄まじい進歩を目の当たりにしてきた光干渉断層計（optical coherence tomography：OCT）の発展と重ねて，OCTアンギオグラフィ（OCT angiography：OCTA）の将来を予測し，併せてOCTAに関する最新の研究についても紹介していく。また，当科で開発したEn face画像の脈絡膜の自動層判定ソフトウェアについても解説する。

参考文献

1）Poddar R, Migacz JV, Schwartz DM et al：Challenges and advantages in wide-field optical coherence tomography angiography imaging of the human retinal and choroidal vasculature at 1.7-MHz A-scan rate. J Biomed Opt 22：1-14, 2017

2）Salas M, Augustin M, Felberer F et al：Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye. Biomed Opt Express 9：1871-1892, 2018

3）Uji A, Balasubramanian S, Lei J et al：Choriocapillaris imaging using multiple En Face optical coherence tomography angiography image averaging. JAMA Ophthalmol 135：1197-1204, 2017

4）Campbell JP, Zhang M, Hwang TS et al：Detailed vascular anatomy of the human retina by projection-resolved optical coherence tomography angiography. Sci Rep 7：42201, 2017

5）Shin JW, Sung KR, Lee JY et al：Optical coherence tomography angiography vessel density mapping at various retinal layers in healthy and normal tension glaucoma eyes. Graefes Arch Clin Exp Ophthalmol 255：1193-1202, 2017

6）Dupas B, Minvielle W, Bonnin S et al：Association between vessel density and visual acuity in patients with diabetic retinopathy and poorly controlled type 1 diabetes. JAMA Ophthalmol 136：721-728, 2018

7）Shiihara H, Terasaki H, Sonoda S et al：Evaluation of shape of foveal avascular zone by optical coherence tomography angiography in eyes with branch retinal vein occlusion. J Vitreoretin Dis 2：138-145, 2018

8）Shiihara H, Sakamoto T, Yamashita T et al：Reproducibility and differences in area of foveal avascular zone measured by three different optical coherence tomographic angiography instruments. Sci Rep 7：9853, 2017

9）Shiihara H, Terasaki H, Sonoda S et al：Objective evaluation of size and shape of superficial foveal avascular zone in normal subjects by optical coherence tomography angiography. Sci Rep 8：10143, 2018

10）Kinoshita T, Mitamura Y, Mori T et al：Changes in choroidal structures in eyes with chronic central serous chorioretinopathy after half-dose photodynamic therapy. PLoS One 11：e0163104, 2016

11）Sonoda S, Sakamoto T, Kuroiwa N et al：Structural changes of inner and outer choroid in central serous chorioretinopathy determined by optical coherence tomography. PLoS One 11：e0157190, 2016

12）Shiihara H, Sonoda S, Terasaki H et al：Automated segmentation of En face choroidal images obtained by optical coherent tomography by machine learning. Jpn J Ophthalmol. （in press）