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文献概要
連載 今月の話題
近視進行抑制—最近の動向
著者: 平岡孝浩1
所属機関: 1筑波大学医学医療系眼科
ページ範囲:P.979 - P.989
文献購入ページに移動 近視進行抑制治療の確立は世界的にも最重要かつ急務の課題の1つであり,将来的なquality of vision(QOV),quality of life(QOL)を守るという観点のみならず,医療経済的な観点からも社会へ及ぼす影響はきわめて大きく,研究者が総力を挙げて取り組むべきテーマである。本稿では近年の近視研究に関して臨床研究を中心としてレビューし,その潮流について解説する。
参考文献
1)Dolgin E:The myopia boom. Nature 519(7543):276-278, 2015
2)Vitale S, Sperduto RD, Ferris FL 3rd:Increased prevalence of myopia in the United States between 1971-1972 and 1999-2004. Arch Ophthalmol 127:1632-1639, 2009
3)Holden BA, Fricke TR, Wilson DA et al:Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology 123:1036-1042, 2016
4)Flitcroft DI:The complex interactions of retinal, optical and environmental factors in myopia aetiology. Prog Retin Eye Res 31:622-660, 2012
5)Yamada M, Hiratsuka Y, Roberts CB et al:Prevalence of visual impairment in the adult Japanese population by cause and severity and future projections. Ophthalmic Epidemiol 17:50-57, 2010
6)Iwase A, Araie M, Tomidokoro A et al:Prevalence and causes of low vision and blindness in a Japanese adult population:the Tajimi Study. Ophthalmology 113:1354-1362, 2006
7)Solouki AM, Verhoeven VJ, van Duijn CM et al:A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet 42:897-901, 2010
8)Hysi PG, Young TL, Mackey DA et al:A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. Nat Genet 42:902-905, 2010
9)Kiefer AK, Tung JY, Do CB et al:Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia. PLoS Genet 9:e1003299, 2013
10)Verhoeven VJ, Hysi PG, Wojciechowski R et al:Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet 45:314-318, 2013
11)Fan Q, Verhoeven VJ, Wojciechowski R et al:Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nat Commun 7:11008, 2016
12)Jones LA, Sinnott LT, Mutti DO et al:Parental history of myopia, sports and outdoor activities, and future myopia. Invest Ophthalmol Vis Sci 48:3524-3532, 2007
13)Sherwin JC, Reacher MH, Keogh RH et al:The association between time spent outdoors and myopia in children and adolescents:a systematic review and meta-analysis. Ophthalmology 119:2141-2151, 2012
14)Xiong S, Sankaridurg P, Naduvilath T et al:Time spent in outdoor activities in relation to myopia prevention and control:a meta-analysis and systematic review. Acta Ophthalmol 95:551-566, 2017
15)Yazar S, Hewitt AW, Black LJ et al:Myopia is associated with lower vitamin D status in young adults. Invest Ophthalmol Vis Sci 55:4552-4559, 2014
16)Choi JA, Han K, Park YM et al:Low serum 25-hydroxyvitamin D is associated with myopia in korean adolescents. Invest Ophthalmol Vis Sci 55:2041-2047, 2014
17)Cohen Y, Belkin M, Yehezkel O et al:Dependency between light intensity and refractive development under light-dark cycles. Exp Eye Res 92:40-46, 2011
18)Karouta C, Ashby RS:Correlation between light levels and the development of deprivation myopia. Invest Ophthalmol Vis Sci 56:299-309, 2015
19)Torii H, Ohnuma K, Kurihara T et al:Violet light transmission is related to myopia progression in adult high myopia. Sci Rep 7:14523. doi:10.1038/s41598-017-09388-7, 2017
20)Torii H, Kurihara T, Seko Y et al:Violet light exposure can be a preventive strategy against myopia progression. Ebiomedicine 15:210-219, 2017
21)Chua WH, Balakrishnan V, Chan YH et al:Atropine for the treatment of childhood myopia. Ophthalmology 113:2285-2291, 2006
22)Chia A, Chua WH, Cheung YB et al:Atropine for the treatment of childhood myopia:safety and efficacy of 0.5%, 0.1%, and 0.01% doses(Atropine for the Treatment of Myopia 2). Ophthalmology 119:347-354, 2012
23)Chia A, Lu QS, Tan D:Five-Year clinical trial on atropine for the treatment of myopia 2:myopia control with atropine 0.01% eyedrops. Ophthalmology 123:391-399, 2016
24)Schwahn HN, Kaymak H, Schaeffel F:Effects of atropine on refractive development, dopamine release, and slow retinal potentials in the chick. Vis Neurosci 17:165-176, 2000
25)Gwiazda J, Thorn F, Bauer J et al:Myopic children show insufficient accommodative response to blur. Invest Ophthalmol Vis Sci 34:690-694, 1993
26)Gwiazda J, Hyman L, Hussein M et al:A randomized clinical trial of progressive addition lenses versus single vision lenses on the progression of myopia in children. Invest Ophthalmol Vis Sci 44:1492-1500, 2003
27)Gwiazda JE, Hyman L, Norton TT et al:Accommodation and related risk factors associated with myopia progression and their interaction with treatment in COMET children. Invest Ophthalmol Vis Sci 45:2143-2151, 2004
28)Hasebe S, Ohtsuki H, Nonaka T et al:Effect of progressive addition lenses on myopia progression in Japanese children:a prospective, randomized, double-masked, crossover trial. Invest Ophthalmol Vis Sci 49:2781-2789, 2008
29)長谷部 聡:眼鏡による近視進行防止.再考!近視メカニズム—実臨床のために—OCULISTA 4:60-66,2013
30)Smith EL 3rd, Kee CS, Ramamirtham R et al:Peripheral vision can influence eye growth and refractive development in infant monkeys. Invest Ophthalmol Vis Sci 46:3965-72, 2005
31)Kanda H, Oshika T, Hiraoka T et al:Effect of spectacle lenses designed to reduce relative peripheral hyperopia on myopia progression in Japanese children:a 2-year multicenter randomized controlled trial. Jpn J Ophthalmol 62:537-543, 2018
32)Kakita T, Hiraoka T, Oshika T:Influence of overnight orthokeratology on axial elongation in childhood myopia. Invest Ophthalmol Vis Sci 52:2170-2174, 2011
33)Hiraoka T, Kakita T, Okamoto F et al:Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia:a 5-year follow-up study. Invest Ophthalmol Vis Sci 53:3913-3919, 2012
34)Cho P, Cheung SW:Retardation of myopia in Orthokeratology(ROMIO)study:a 2-year randomized clinical trial. Invest Ophthalmol Vis Sci 53:7077-7085, 2012
35)Li SM, Kang MT, Wu SS et al:Efficacy, safety and acceptability of orthokeratology on slowing axial elongation in myopic children by meta-analysis. Curr Eye Res 41:600-608, 2016
36)Sun Y, Xu F, Zhang T et al:Orthokeratology to control myopia progression:a meta-analysis. PLoS One 10:e0124535, 2015
37)Si JK, Tang K, Bi HS et al:Orthokeratology for myopia control:a meta-analysis. Optom Vis Sci 92:252-257, 2015
38)Wen D, Huang J, Chen H et al:Efficacy and acceptability of orthokeratology for slowing myopic progression in children:a systematic review and meta-analysis. J Ophthalmol 2015:360806, 2015
39)Hiraoka T, Sekine Y, Okamoto F et al:Safety and efficacy following 10-years of overnight orthokeratology for myopia control. Ophthalmic Physiol Opt 38:281-289, 2018
40)Sankaridurg P, Holden B, Smith E 3rd et al:Decrease in rate of myopia progression with a contact lens designed to reduce relative peripheral hyperopia:one-year results. Invest Ophthalmol Vis Sci 52:9362-9367, 2011
41)Anstice NS, Phillips JR:Effect of dual-focus soft contact lens wear on axial myopia progression in children. Ophthalmology 118:1152-1161, 2011
42)Fujikado T, Ninomiya S, Kobayashi T et al:Effect of low-addition soft contact lenses with decentered optical design on myopia progression in children:a pilot study. Clin Ophthalmol 8:1947-1956, 2014
43)Chamberlain P, Back A, Lazon P et al:3 year effectiveness of a dual-focus 1 day soft contact lens for myopia control. Presented at the 40th British Contact Lens Association Clinical Conference and Exhibition;10 June 2017;Liverpool, United Kingdom
44)Cooper J, O'Connor B, Watanabe R et al:Case series analysis of myopic progression control with a unique extended depth of focus multifocal contact lens. Eye Contact Lens 44:e16-e24, 2018
45)Kinoshita N, Konno Y, Hamada N et al:Additive effects of orthokeratology and atropine 0.01% ophthalmic solution in slowing axial elongation in children with myopia:first year results. Jpn J Ophthalmol 62:544-553, 2018
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