臨床眼科74巻8号

2020年08月発行

連載 今月の話題

遺伝子治療による視機能再建

著者： 冨田浩史¹ 菅野江里子¹

所属機関： ¹岩手大学理工学部生命コース

ページ範囲：P.941 - P.948

　当研究室で開発したチャネルロドプシン遺伝子（mVChR1）は，幅広い可視光に応答し細胞内に陽イオンを透過させる機能をもつ。mVChR1を神経節細胞に導入し発現させることで，視細胞を利用しない光受容システムを作り出すことが可能である。本稿では，mVChR1を用いた視覚再生のための遺伝子治療の原理とその概要を解説する。

参考文献

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