臨床眼科75巻12号

2021年11月発行

特集 網膜色素変性のアップデート 【治療法開発研究の最前線】

網膜色素変性における再生医療

著者： 万代道子¹

所属機関： ¹理化学研究所生命機能科学研究センター網膜再生医療研究開発プロジェクト

ページ範囲：P.1491 - P.1497

●ES細胞やiPS細胞から究極的な生体材料ともいえる網膜色素上皮（RPE）細胞や網膜組織・細胞が用意できるようになった。

●ES/iPS細胞由来のRPE細胞については複数の臨床研究や治験が海外で行われてきており，安全性の確認の段階から，適応の拡大および有効性を検証する段階へと進んでいる。

●ES/iPS細胞由来の網膜組織を用いた移植による視機能の再建は動物で検証されており，国内での臨床研究も開始された。

参考文献

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