文献詳細
連載 国際スタンダードを理解しよう! 近視診療の最前線・33
文献概要
◆近視発症にかかわる遺伝子はGJD2 など500領域以上も発見されている。
◆近視性牽引黄斑症,後部ぶどう腫,近視性脈絡膜新生血管の発症にかかわる遺伝子はまだ発見されていない。
◆近視性網脈絡膜萎縮の発症にかかわる遺伝子としてはCCDC102B 遺伝子が最近発見された。
◆近視性牽引黄斑症,後部ぶどう腫,近視性脈絡膜新生血管の発症にかかわる遺伝子はまだ発見されていない。
◆近視性網脈絡膜萎縮の発症にかかわる遺伝子としては
参考文献
1)Hysi PG, Choquet H, Khawaja AP et al:Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. Nat Genet 52:401-407, 2020
2)Tideman JWL, Pärssinen O, Haarman AEG et al:Evaluation of shared genetic susceptibility to high and low myopia and hyperopia. JAMA Ophthalmol 139:601-609, 2021
confers risk of low vision and blindness in high myopia. Nat Commun 9:1782, 2018
4)Wakazono T, Yamashiro K, Miyake M et al:Association between eye shape and myopic traction maculopathy in high myopia. Ophthalmology 123:919-921, 2016
5)Miyake M, Yamashiro K, Akagi-Kurashige Y et al:Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. PLoS One 9:e107923, 2014
6)Fernandez-Robredo P, Maestre SR, Zarranz-Ventura J et al:Myopic choroidal neovascularization genetics. Ophthalmology 115:1632, 2008
7)Nakanishi H, Gotoh N, Yamada R et al:ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population. Eye(Lond) 24:1078-1084, 2010
8)Hayashi H, Yamashiro K, Nakanishi H et al:Association of 15q14 and 15q25 with high myopia in Japanese. Invest Ophthalmol Vis Sci 52:4853-4858, 2011
9)Akagi-Kurashige Y, Kumagai K, Yamashiro K et al:Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes. Invest Ophthalmol Vis Sci 53:2349-2353, 2012
10)Leveziel N, Yu Y, Reynolds R et al:Genetic factors for choroidal neovascularization associated with high myopia. Invest Ophthalmol Vis Sci 53:5004-5009, 2012
11)Miyake M, Yamashiro K, Nakanishi H et al:Evaluation of pigment epithelium-derived factor and complement factor Ⅰ polymorphisms as a cause of choroidal neovascularization in highly myopic eyes. Invest Ophthalmol Vis Sci 54:4208-4212, 2013
掲載誌情報