臨床眼科78巻13号

2024年12月発行

特集 生活習慣と眼の病気のビミョーな関係。

食習慣から考える老視・白内障予防

著者： 久保江理¹

所属機関： ¹金沢医科大学眼科学講座

ページ範囲：P.1472 - P.1476

文献概要

●老視・白内障は，酸化ストレス，糖化ストレス，炎症が3大要因。

●抗酸化物質の摂取と糖化ストレスの回避が老視・白内障予防にとって重要。

●抗酸化・抗糖化・抗炎症を意識した食習慣（野菜，果物，魚の摂取）が白内障予防に効果的。

参考文献

1）Moeller SM, Voland R, Tinker L, et al：Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health Initiative. Arch Ophthalmol 126：354-364, 2008

2）Sideri O, Tsaousis KT, Li HJ, et al：The potential role of nutrition on lens pathology：a systematic review and meta-analysis. Surv Ophthalmol 64：668-678, 2019

3）Liu XH, Yu RB, Liu R, et al：Association between lutein and zeaxanthin status and the risk of cataract：a meta-analysis. Nutrients 6：452-465, 2014

4）Nagashima H, Sasaki N, Amano S, et al：Oral administration of resveratrol or lactic acid bacterium improves lens elasticity. Sci Rep 11：2174, 2021

5）Nakazawa Y, Doki Y, Sugiyama Y, et al：Effect of alpha-glucosyl-hesperidin consumption on lens sclerosis and presbyopia. Cells 10：382, 2021

6）Ishikawa S, Hashizume K, Nishigori H, et al：Effect of astaxanthin on cataract formation induced by glucocorticoids in the chick embryo. Curr Eye Res 40：535-540, 2015

7）Kubo E：Aging of the crystalline lens from the viewpoint of anti-glycation and anti-oxidation. Glycative Stress Research 7：283-286, 2020

8）Christen WG, Liu S, Schaumberg DA, et al：Fruit and vegetable intake and the risk of cataract in women. Am J Clin Nutr 81：1417-1422, 2005

9）Adachi A, Sawada N, Yuki K, et al：Intake of vegetables and fruits and the risk of cataract incidence in a Japanese population：The Japan Public Health Center-Based Prospective Study. J Epidemiol 31：21-29, 2021

10）Falkowska M, Młynarczyk M, Micun Z, et al：Influence of diet, dietary products and vitamins on age-related cataract incidence：a systematic review. Nutrients 15：4585, 2023

. Evid Based Complement Alternat Med 2021：9902211, 2021