Symposium On Active Transport
Effects of Metabolic Inhibitors and Ouabain on Transport of Ions through Frog Skin
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It might reasonably be expected that various metabolic inhibitors inhibit active transport of matter, a process which requires energy derived from cellular metabolism.However, Schatzmann13) showed several years ago that certain cardiac glycosides and aglycones inhibited selectively the active transport of Na and K in human red cells.Since then these drugs have been studied considerably with respect to the inhibitory action on active transport in several living membranes.
Since the work of Ussing and Zerahn15), the active Na transport across the frog skin has been studied extensively because with this material it is relatively easy to obtain various information about the active transport of ions.