臨床泌尿器科60巻10号

2006年09月発行

特集 Female urology

更年期と排尿障害

著者： 小川輝之¹ 石塚修¹ 西澤理¹

所属機関： ¹信州大学医学部泌尿器科

ページ範囲：P.725 - P.728

文献概要

要旨　更年期障害はエストロゲンの持続的低下によりさまざまな病態を引き起こすことが知られている。泌尿器疾患では，尿意切迫感，頻尿，尿失禁が更年期女性でよくみられる症状である。エストロゲンの低下と尿失禁との因果関係は基礎実験ではいくつか報告されている。臨床的には，エストロゲンの補充療法は閉経期女性の切迫性尿失禁，反復性尿路感染症に対して有効であったとの報告や，低用量のエストロゲン局所投与は反復性尿路感染症について有効であったとの報告がある。しかしながら，エストロゲンの補充療法がこれら排尿障害に有効であるかは，明確には結論が出ていないのが現状である。

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