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文献詳細

雑誌文献

臨床泌尿器科60巻11号

2006年10月発行

セミナー 下部尿路症状(LUTS)診療の最前線 2

過活動膀胱の治療

著者: 関聡1 井川靖彦2 西沢理2

所属機関: 1信州大学医学部医学研究科泌尿器科学領域産学連携学講座 2同 泌尿器科学講座・泌尿器科学領域産学連携学講座

ページ範囲:P.817 - P.821

文献概要

 要約:過活動膀胱の初期治療として行動療法や薬物療法がある。薬物療法の主体は抗コリン薬である。薬物療法に反応しない症例に対しては,neuromodulationやボツリヌストキシンの膀胱壁内注入療法などが行われるが,その治療効果についてはさらに検討が必要である。

参考文献

1)Andersson K-E, Appell R and Awad S:Pharmacological treatment of urinary incontinence. In:Incontinence. edited by Abrams P, et al. Plymbridge Distributers Ltd, Plymouth, pp697-754, 2002
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3)Goode PS, Burgio KL, Locher JL, et al:Urodynamic changes associated with behavioral and drug treatment of urge incontinence in older women. J Am Geriatr Soc 50:808-816, 2002
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9)Chapple CR, Martinez-Garcia R, Selvaggi L, et al:A comparison of the efficacy and tolerability of solifenacin succinate and extended release tolterodine at treating overactive bladder syndrome:results of the STAR trial. Eur Urol 48:464-470, 2005
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11)Giannantoni A, Di Stasi SM, Stephen RL, et al:Intravesical capsaicin versus resiniferatoxin in patients with detrusor hyperreflexia:a prospective randomized study. J Urol 167:1710-1714, 2002
12)de Seze M, Wiart L, de Seze MP, et al:Intravesical capsaicin versus resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients:a double-blind, randomized, controlled study. J Urol 171:251-255, 2004
13)Kuo HC:Effectiveness of intravesical resiniferatoxin for anticholinergic treatment refractory detrusor overactivity due to nonspinal cord lesions. J Urol 170:835-839, 2003
14)Silva C, Ribeiro MJ and Cruz F:The effect of intravesical resiniferatoxin in patients with idiopathic detrusor instability suggests that involuntary detrusor contractions are triggered by C-fiber input. J Urol 168:575-579, 2002
15)Dykstra DD, Sidi AA, Scott AB, et al:Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients. J Urol 139:919-922, 1988
16)Reitz A, Stohrer M, Kramer G, et al:European experience of 200 cases treated with botulinum-A toxin injections into the detrusor muscle for urinary incontinence due to neurogenic detrusor overactivity. Eur Urol 45:510-515, 2004
17)Schulte-Baukloh H, Weiss C, Stolze T, et al:Botulinum-A toxin for treatment of overactive bladder without detrusor overactivity:urodynamic outcome and patient satisfaction. Urology 66:82-87, 2005
18)Rapp, DE, Lucioni A, Katz EE, et al:Use of botulinum-A toxin for the treatment of refractory overactive bladder symptoms:an initial experience. Urology 63:1071-1075, 2004
19)Ho MH, Lin LL, Haessler AL, et al:Intravesical injection of botulinum toxin for the treatment of overactive bladder. Curr Opin Obstet Gynecol 17:512-518, 2005
20)日本排尿機能学会(編):過活動膀胱診療ガイドライン.Blackwell Publishing,東京,2005
21)横山光彦,公文裕巳:ボツリヌス毒素.排尿障害プラクティス,Vol. 13,No. 2,pp82-87,2005

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1332

印刷版ISSN:0385-2393

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