臨床泌尿器科64巻7号

2010年06月発行

特集 抗癌剤治療の副作用とそのコントロール

各論

―抗癌剤の副作用4―皮膚・口腔粘膜障害

著者： 宮崎淳¹

所属機関： ¹筑波大学大学院人間総合科学研究科臨床医学系泌尿器科

ページ範囲：P.483 - P.489

文献概要

要旨　口腔粘膜炎は抗癌剤治療時によくみられる副作用である。口腔粘膜炎は感染や死亡のリスクファクターであり，口腔ケアなどの予防が第一であるが，海外ではケラチノサイト増殖因子やL-glutamineなどの有効な予防法の研究も進んでいる。また，種々の皮膚障害，脱毛，浮腫などの皮膚症状は抗癌剤治療において頻度の高い副作用であるものの，重篤なものが稀であった。しかし，最近の分子標的薬使用により手足症候群などの皮膚障害が注目されている。医療者はあらかじめこれらの副作用についての知識を持って患者に接する必要がある。

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