臨床泌尿器科65巻7号

2011年06月発行

綜説

求心性神経泌尿器科学 新たな概念の提案

著者： 飯島和芳¹ 石塚修² 西沢理²

所属機関： ¹長野市民病院泌尿器科 ²信州大学医学部泌尿器科学教室

ページ範囲：P.439 - P.445

要旨　近年，尿路知覚とそれに関連する疾患に大きな関心が集まっている^1～3）。過活動膀胱^3～6），間質性膀胱炎^7），脊髄損傷^8）の病態の背景には，膀胱求心性神経活動の亢進が関与していることが示され，膀胱求心性神経活動の亢進を抑える治療に焦点が当てられてきている。これらの尿路生殖器系の求心性神経活動と，神経活動の変化が関係する疾患を扱うにあたり，“afferent neurourology”という概念が提唱されるようになった^9,10）。本稿では，この新しく提唱された“afferent neurourology”について概説し，今後の臨床応用への課題を紹介する。

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