臨床泌尿器科69巻1号

2015年01月発行

特集 LOH症候群診療—最近の進歩

テストステロンと排尿機能

著者： 木内寛¹ 宮川康¹ 野々村祝夫¹

所属機関： ¹大阪大学大学院医学系研究科器官制御外科学（泌尿器科）

ページ範囲：P.40 - P.45

文献概要

要旨　中高年期では加齢に伴いテストステロンが低下し，その影響は性機能だけでなく，全身に及び，内臓脂肪の増加，睡眠障害，骨減少などを引き起こす。排尿機能も加齢に伴い，その機能障害が起こり，排尿症状，蓄尿症状，排尿後症状が出現し，QOLを低下させる。現在までの研究からテストステロンが下部尿路に何らかの影響がある可能性が示唆されるが，どの程度関与しているかはまだまだよくわかっておらず，不明な点が多い。今後，さらなる臨床試験や基礎実験が望まれる。

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