臨床泌尿器科69巻8号

2015年07月発行

特集 抗菌薬の選択と上手な使い方！—私の処方箋

反復性・難治性膀胱炎

著者： 栗村雄一郎¹

所属機関： ¹苫小牧泌尿器科・循環器内科

ページ範囲：P.622 - P.628

文献概要

要旨　反復性膀胱炎は6か月に2回以上または1年に3回以上の再発と定義され，bacterial persistenceとreinfectionの2タイプに分けられる。危険因子として若い女性では性交が，閉経後の女性ではエストロゲン減少が重要である。抗菌薬を使用した予防法として，①低量予防投与法，②性交後予防投与法，③セルフスタート療法などがあり，抗菌薬以外ではクランベリージュース，免疫活性療法などが報告されている。難治性膀胱炎では，抗菌薬感受性の再確認と性器感染症も含めた他疾患の除外診断が必要である。

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