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文献詳細

雑誌文献

臨床泌尿器科70巻10号

2016年09月発行

特集 最新泌尿器病理─世界の最先端を学ぶ

膀胱癌の最新知見─変化の始まり

著者: 都築豊徳1

所属機関: 1愛知医科大学医学部病院病理部

ページ範囲:P.737 - P.742

文献概要

▶ポイント

・2016年に発刊されたWHO改訂版での重要な項目および新しい概念を紹介する.

・日本と欧米とで解釈が異なる上皮内癌の概念を述べる.

・近年の研究で多様性が明らかにされてきた尿路上皮癌の分子生物学的側面に基づく分類方法の解説を行う.

参考文献

1) Moch H, Humphrey PA, Ulbright TM, et al (eds) : WHO Classification of Tumours of the Urinary System and Male Genital Organs. Lyon, IARC Publications, 2016
2) Rosenberg JE, Hoffman-Censits J, Powles T, et al : Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy : a single-arm, multicentre, phase 2 trial. Lancet 38 : 1909─1920, 2016
3) Mostofi FK, Sobin LH and Torloni H : Histological Typing of Urinary Bladder Tumours. World Health Orgnanization, Geneva, 1973
4) Epstein JI, Amin MB, Reuter VR, et al : The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Bladder Consensus Conference Committee. Am J Surg Pathol 22 : 1435─1448, 1998
5) Eble JE, Sauter G, Epstein JI, et al : Pathology and Genetics of Tumour of the Urinary System and Male Genital Organs. IRCPress, Lyon, 2004
6) Amin MB, McKenney JK, Paner GP, et al : ICUD-EAU International Consultation on Bladder Cancer 2012 : Pathology. Eur Urol 63 : 16─35, 2013
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10) Amin MB, Ro JY, el-Sharkawy T, et al : Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma. Am J Surg Pathol 18 : 1224─1232, 1994
11) Samaratunga H and Khoo K : Micropapillary variant of urothelial carcinoma of the urinary bladder : a clinicopathological and immunohistochemical study. Histopathology 45 : 55─64, 2004
12) Spaliviero M, Dalbagni G, Bochner BH, et al : Clinical outcome of patients with T1 micropapillary urothelial carcinoma of the bladder. J Urol 192 : 702─707, 2014
13) Guo CC, Dadhania V, Zhang L, et al : Gene Expression Profile of the Clinically Aggressive Micropapillary Variant of Bladder Cancer. Eur Urol 2016〔Epub ahead of print〕
14) Drew PA, Furman J, Civantos F, et al : The nested variant of transitional cell carcinoma : an aggressive neoplasm with innocuous histology. Mod Pathol 9 : 989─994, 1996
15) Cox R and Epstein JI : Large nested variant of urothelial carcinoma : 23 cases mimicking von Brunn nests and inverted growth pattern of noninvasive papillary urothelial carcinoma. Am J Surg Pathol 35 : 1337─1342, 2011
16) Damrauer JS, Hoadley KA, Chism DD, et al : Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology. Proc Natl Acad Sci U S A 111 : 3110─3115, 2014
17) Choi W, Porten S, Kim S, et al : Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell 25 : 152─165, 2014
18) Cancer Genome Atlas Research Network : Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 507 : 315─322, 2014

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1332

印刷版ISSN:0385-2393

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