icon fsr

文献詳細

雑誌文献

臨床泌尿器科70巻10号

2016年09月発行

特集 最新泌尿器病理─世界の最先端を学ぶ

新WHOで変わる陰茎癌病理

著者: 内田克典1

所属機関: 1三重大学大学院医学系研究科腫瘍病理学

ページ範囲:P.768 - P.775

文献概要

▶ポイント

・扁平上皮癌の組織分類にHPV感染の有無が採用され,従来の8亜型から15亜型に細分化された.

・前駆病変として,従来のintraepithelial neoplasiaからPenile intraepithelial neoplasiaに改変され,SCCの各組織亜型に対応するように詳細な組織亜型が採用された.

参考文献

1) Moch H, Humphrey PA, Ulbright TM, et al : WHO Classification of Tumors of the Urinary System and Male Genital Organs. pp259─286, IARC, Lyon, 2016
2) Eble JN, Sauter G, Epstein JI, et al : Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs. pp279─298, IARCPress, Lyon, 2004
3) Sanchez DF, Soares F, Alvarado-Cabrero I, et al : Pathological factors, behavior, and histological prognostic risk groups in subtypes of penile squamous cell carcinomas (SCC).Semin Daign Pathol 32 : 222─231, 2015
4) Velazquez EF and Cubilla AL : Lichen sclerosus in 68 patients with squamous cell carcinoma of the penis : frequent atypias and correlation with special carcinoma variants suggests a precancerous role. Am J Surg Pathol 27 : 1448─1453, 2003
5) Cubilla AL, Velazquez EF and Young RH : Pseudohyperplastic squamous cell carcinoma of the penis associated with lichen sclerosus. An extremely well-differentiated, nonverruciform neoplasm that preferentially affects the foreskin and is frequently misdiagnosed : a report of 10 cases of a distinctive clinicopathologic entity. Am J Surg Pathol 28 : 895─900, 2004
6) Cunha IW, Guimaraes GC, Soares F, et al : Pseudoglandular (adenoid, acantholytic) penile squamous cell carcinoma : a clinicopathologic and outcome study of 7 patients. Am J Surg Pathol 33 : 551─555, 2009
7) Barreto JE, Velazquez EF, Ayala E, et al : Carcinoma cuniculatum : a distinctive variant of penile squamous cell carcinoma : report of 7 cases. Am J Surg Pathol 31 : 71─75, 2007
8) Cubilla AL, Lloveras B, Alemany L, et al : Basaloid squamous cell carcinoma of the penis with papillary features : a clinicopathologic study of 12 cases. Am J Surg Pathol 36 : 869─875, 2012
9) Chaux A, Tamboli P, Ayala A, et al : Warty-basaloid carcinoma : clinicopathological features of a distinctive penile neoplasm. Report of 45 cases. Mod Pathol 23 : 896─904, 2010
10) Liegl B and Regauer S : Penile clear cell carcinoma : a report of 5 cases of a distinct entity. Am J Surg Pathol 28 : 1513─1517, 2004
11) Sanchez DF, Rodriguez IM, Piris A, et al : Clear Cell Carcinoma of the Penis : an HPV-related Variant of Squamous Cell Carcinoma : A Report of 3 Cases. Am J Surg Pathol 40 : 917─922, 2016
12) Kazakov DV, Nemcova J, Mikyskova I, et al : Absence of Epstein-Barr virus, human papillomavirus, and simian virus 40 in patients of central european origin with lymphoepithelioma-like carcinoma of the skin. Am J Dermatopathol 29 : 365─369, 2007
13) Oertell J, Caballero C, Iglesias M, et al : Differentiated precursor lesions and low-grade variants of squamous cell carcinomas are frequent findings in foreskins of patients from a region of high penile cancer incidence. Histopathology 58 : 925─933, 2011
14) Chaux A, Velazquez EF, Amin A, et al : Distribution and characterization of subtypes of penile intraepithelial neoplasia and their association with invasive carcinomas : a pathological study of 139 lesions in 121 patients. Hum Pathol 43 : 1020─1027, 2012
15) Bethune G, Campbell G, Rocker A, et al : Clinical and pathologic factors of prognostic significance in penile squamous cell carcinoma in a North American population. Urology 79 : 1092─1097, 2012
16) Gunia S, Erbersdobler A, Hakenberg OW, et al : p16 (INK4a) is a marker of good prognosis for primary invasive penile squamous cell carcinoma : a multi-institutional study. J Urol 187 : 899─907, 2012
17) Epstein JI, Cubilla AL, Humphery PA, et al : Tumors of the Prostate Gland, Seminal Vesicles, Penis, and Scrotum (AFIP atlas of tumor pathology : series 4). pp405─612, ARP and AFIP, Washington DC, 2011

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1332

印刷版ISSN:0385-2393

雑誌購入ページに移動
icon up

本サービスは医療関係者に向けた情報提供を目的としております。
一般の方に対する情報提供を目的としたものではない事をご了承ください。
また,本サービスのご利用にあたっては,利用規約およびプライバシーポリシーへの同意が必要です。

※本サービスを使わずにご契約中の電子商品をご利用したい場合はこちら