臨床泌尿器科71巻13号

2017年12月発行

綜説

尿路結石の形成機序と治療への展望

著者： 安井孝周¹

所属機関： ¹名古屋市立大学大学院医学研究科腎・泌尿器科学分野

ページ範囲：P.1039 - P.1046

文献概要

要旨

　尿路結石の手術治療は，内視鏡手術の発達によりstone freeが可能となってきた．しかし，再発が多い尿路結石治療の目標は，その成因の検索による再発予防である．尿路結石の形成機序では細胞傷害からRandall'sプラークが形成され，シュウ酸カルシウム結石に成長することが明らかになってきた．尿路結石は遺伝因子に加えて食生活を中心とした環境因子が重なる生活習慣病である．尿路結石の疼痛発作は，将来にわたる健康人生への分岐点であることを啓発いただきたい．

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