臨床泌尿器科72巻10号

2018年09月発行

特集 停留精巣のすべて─小児から成人への架け橋

〈基礎研究〉

停留精巣の基礎研究の歴史─停留精巣モデルを用いた造精機能障害に関する研究を中心に

著者： 水野健太郎¹ 西尾英紀¹ 林祐太郎¹

所属機関： ¹名古屋市立大学大学院医学研究科 小児泌尿器科学分野

ページ範囲：P.826 - P.835

文献概要

▶ポイント

・停留精巣の基礎研究は18世紀に始まった解剖学的なものから，現在の分子生物学的アプローチを用いた研究まで非常に幅広く行われている．

・基礎研究は，①精巣下降メカニズム，②造精機能障害の原因・治療，③悪性腫瘍の発生機序に関する3つに大別される．

・停留精巣の完全な動物モデルは存在しないため，研究目的を明確にして評価する必要がある．

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