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雑誌文献

臨床泌尿器科73巻10号

2019年09月発行

特集 腎移植臨床の進歩―集学的治療における泌尿器科医の役割を再考する

〈最近のトピックス〉

小児腎移植における新展開―小児ドナーからの脳死下多臓器提供(en bloc腎移植)および小児レシピエントの尿路異常への対応

著者: 村松真樹1 宍戸清一郎1

所属機関: 1東邦大学医学部腎臓学講座

ページ範囲:P.757 - P.761

文献概要

▶ポイント

・6歳未満の小児ドナーからの腎臓提供では,両腎を1人へ移植するen bloc腎移植の選択が可能である.

・en bloc腎移植では血管吻合にドナーの大動脈と下大静脈が主に用いられる.

・尿路障害を有する小児への腎移植は,適正な時期を見定めて計画的な治療介入が必要である.

参考文献

1) 日本臓器移植ネットワーク : 腎臓移植希望者 (レシピエント) 選択基準. https://www.jotnw.or.jp/jotnw/law_manual/pdf/rec-kidney.pdf
2) Kayler LK, Magliocca J, Kim RD, et al : Single kidney transplantation from young pediatric donors in the United States. Am J Transplant 9 : 2745-2751, 2009
3) Sureshkumar KK, Patel AA, Arora S, et al : When is it reasonable to split pediatric en bloc kidneys for transplantation into two adults? Transplant Proc 42 : 3521-3523, 2010
4) Tittelbach-Helmrich D, Drognitz O, Pisarski P, et al : Single kidney transplantation from young pediatric donors in the United States. Am J Transplant 10 : 2179 ; author reply 2180, 2010
5) Nghiem DD, Hsia S and Schlosser JD : Growth and function of en bloc infant kidney transplants : a preliminary study. J Urol 153 : 326-329, 1995
6) Winnicki E, Dharmar M, Tancredi D, et al : Comparable Survival of En Bloc versus Standard Donor Kidney Transplants in Children. J Pediatr 173 : 169-174, 2016
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8) Yaffe HC, Friedmann P and Kayler LK : Very small pediatric donor kidney transplantation in pediatric recipients. Pediatr Transplant 21, 2017
9) 日本移植学会 : 腎臓採取マニュアル. http://www.asas.or.jp/jst/pdf/manual/006.pdf
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11) Amante AJ and Kahan BD : En bloc transplantation of kidneys from pediatric donors. J Urol 155 : 852-856 ; discussion 856-857, 1996
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27) Riley P, Marks SD, Desai DY, et al : Challenges Facing Renal Transplantation in Pediatric Patients With Lower Urinary Tract Dysfunction. Transplantation 89 : 1299-1307, 2010

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1332

印刷版ISSN:0385-2393

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