文献詳細
特集 ここまで見える! 泌尿器科における可視化の進歩
〈細胞の可視化〉
文献概要
▶ポイント
・CTCの臨床応用には,治療選択の補助診断や予後予測マーカーが考えられる.
・CTCクラスターはCTC全体の2〜5%を占め,CTC単独よりもはるかに癌転移を引き起こしやすい.
・CTCの臨床応用には,治療選択の補助診断や予後予測マーカーが考えられる.
・CTCクラスターはCTC全体の2〜5%を占め,CTC単独よりもはるかに癌転移を引き起こしやすい.
参考文献
1) Allard WJ, Matera J, Miller MC, et al : Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clin Cancer Res 10 : 6897-6904, 2004
2) Powell AA, Talasaz AH, Zhang H, et al : Single cell profiling of circulating tumor cells : transcriptional heterogeneity and diversity from breast cancer cell lines. PLoS One 7 : e33788, 2012
3) Ross JS and Slodkowska EA : Circulating and disseminated tumor cells in the management of breast cancer. Am J Clin Pathol 132 : 237-245, 2009
4) Nagrath S, Sequist LV, Maheswaran S, et al : Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450 : 1235-1239, 2007
5) Vona G, Sabile A, Louha M, et al : Isolation by size of epithelial tumor cells : a new method for the immunomorphological and molecular characterization of circulating tumor cells. Am J Pathol 156 : 57-63, 2000
6) Desitter I, Guerrouahen BS, Benali-Furet N, et al : A new device for rapid isolation by size and characterization of rare circulating tumor cells. Anticancer Res 31 : 427-441, 2011
7) Hou HW, Warkiani ME, Khoo BL, et al : Isolation and retrieval of circulating tumor cells using centrifugal forces. Sci Rep 3 : 1259, 2013
8) Rosenberg R, Gertler R, Friederichs J, et al : Comparison of two density gradient centrifugation systems for the enrichmen of disseminated tumor cells in blood. Cytometry 49 : 150-158, 2002
, a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood. Biomicrofluidics 6 : 024133, 2012
10) Ozkumur E, Shah AM, Ciciliano JC, et al : Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med 5 : 179ra47, 2013
11) Karabacak NM, Spuhler PS, Fachin F, et al : Microfluidic, marker-free isolation of circulating tumor cells from blood samples. Nat Protoc 9 : 694-710, 2014
12) 最上聡文, 森本篤史, 飯島和樹, 他 : 誘電泳動を利用した血中希少がん細胞の検出・解析システムの開発. 東ソー研究・技術報告書58 : 3-12, 2014
13) 森本篤史, 飯島和樹, 最上聡文, 他 : 転移性乳がん患者からの血中循環がん細胞の検出と1細胞遺伝子解析. 東ソー研究・技術報告書59 : 3-9, 2015
14) 桶川隆嗣 : 入門!! リキッドバイオプシー. 泌外32 : 3-18, 2019
15) Okegawa T, Ninomiya N, Masuda K, et al : AR-V7 in circulating tumor cell clusters as predictive biomarker of abiraterone acetate and enzalutamide treatment in castration-resistant prostate cancer patients. Prostate 78 : 576-582, 2018
16) Josefsson A, Larsson K, Månsson M, et al : Circulating tumor cells mirror bone metastatic phenotype in prostate cancer. Oncotarget 9 : 29403-29413, 2018
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